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Mänskliga neurala Organoider för att studera hjärn cancer och neurodegenerativa sjukdomar
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1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine,University of Geneva, 2Department of Pathology and Immunology, University Medical Center,University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring,Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO,University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics,Geneva University Hospitals
Capitoli
- 00:04Titolo
- 00:52hESC-derived Neural Organoids for Glioblastoma Multiforme Studies
- 04:39hESC-derived Dopaminergic Organoids for Parkinson s Disease Studies
- 08:12Results: Generation of Dopaminergic Neural Organoid and Electrophysiological and Morphological Analysis
- 09:14Conclusion
Denna studie introducerar och beskriver protokoll för att härleda två specifika mänskliga neurala organoider som en relevant och korrekt modell för att studera 1) mänskliga glioblastoma utveckling inom mänskliga neurala organoider uteslutande hos människor och 2) neuron dopaminerga differentiering generera en tredimensionell Organoid.
