Rivista
/
Neuroscienze
/
Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
JoVE Journal
Neuroscienze
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Neuroscienze
Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat

Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat

DOI:
10.3791/59738-v

•

06:44 min

•

June 26, 2019

•

,
1Department of Neurosciences, Faculté de Médecine,Université de Montréal, 2Hôpital du Sacré-Cœur de Montréal, 3Groupe de Recherche sur le Système Nerveux Central (GRSNC),Université de Montréal

Capitoli

  • 00:04Titolo
  • 00:32Thoracic Hemisection
  • 03:23Open-Field Testing and Locomotor Performance Scoring
  • 05:15Representative Results
  • 06:11Conclusion

Summary

Traduzione automatica

Traduzione automatica

The rat thoracic spinal hemisection is a valuable and reproducible model of unilateral spinal cord injury to investigate the neural mechanisms of locomotor recovery and treatment efficacy. This article includes a detailed step-by-step guide to perform the hemisection procedure and to assess locomotor performance in an open-field arena.

Tags

Keywords: Spinal Cord HemisectionLocomotor AssessmentRatThoracicLaminectomyLidocaineDura MaterMidlineDissecting KnifeAnterior Spinal Artery

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

check_url/it/59738?article_type=v

Dissection and Culture of Commissural Neurons from Embryonic Spinal Cord
check_url/it/59738?article_type=v

Spinal Cord Electrophysiology II: Extracellular Suction Electrode Fabrication
check_url/it/59738?article_type=v

Spinal Cord Transection in the Larval Zebrafish
check_url/it/59738?article_type=v

An Ex Vivo Laser-induced Spinal Cord Injury Model to Assess Mechanisms of Axonal Degeneration in Real-time
check_url/it/59738?article_type=v

Diffusion Imaging in the Rat Cervical Spinal Cord
check_url/it/59738?article_type=v

Spinal Cord Neurons Isolation and Culture from Neonatal Mice
check_url/it/59738?article_type=v

Imaging Neural Activity in the Primary Somatosensory Cortex Using Thy1-GCaMP6s Transgenic Mice
check_url/it/59738?article_type=v

An In Vivo Duo-color Method for Imaging Vascular Dynamics Following Contusive Spinal Cord Injury
check_url/it/59738?article_type=v

Laminectomy and Spinal Cord Window Implantation in the Mouse
check_url/it/59738?article_type=v

Direct Injection of a Lentiviral Vector Highlights Multiple Motor Pathways in the Rat Spinal Cord

Read Article