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通过电生理场记录研究跨体海马CA1的长期突触可塑性

JoVE Journal
Neuroscienze
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JoVE Journal Neuroscienze

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

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通过电生理场记录研究跨体海马CA1的长期突触可塑性

DOI:

10.3791/59879-v

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14:27 min

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August 11, 2019

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Hannnah Tetteh*¹, Jihwan Lee*¹, Jinho Lee, Jae Geun Kim, Sunggu Yang

¹Department of Biomedical Sciences,City University of Hong Kong, ²Department of Nano-Bioengineering,Incheon National University, ³Division of Life Sciences, College of Life Sciences and Bioengineering,Incheon National University

Capitoli

00:00Titolo
01:00Animal Preparation: Draining of Cerebrospinal Fluid
02:35Animal Preparation: Craniotomy
04:22Data Acquisition: In Vivo
06:06In Vitro Setup
07:10Brain Slicing
11:00Data Acquisition: In Vitro
12:48Risultati
13:43Conclusion

Summary

Traduzione automatica

我们在纵向海马脑切片中使用记录和刺激电极,并在体内背海马区中纵向定位记录和刺激电极,以唤起细胞外的显微电位并演示沿纵向间层 CA1 的长期突触可塑性。

Tags

Keywords: Long-term Synaptic Plasticity Long-term Potentiation Long-term Depression Hippocampus CA1 Electrophysiological Field Recording Longitudinal Orientation Associational Connections Urethane Anesthesia Stereotaxic Surgery Cerebrospinal Fluid Drainage Stimulation And Recording Electrodes Dorsal Hippocampus CA1

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