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Capitoli
- 00:04Introduction
- 01:07Aortic Banding Preparation and Post-Operative Care
- 02:40Aortic Debanding
- 03:36Echocardiography (ECG)
- 05:26Results: Representative Echocardiographic, Pressure Volume, and Histological Assessments of Cardiac Structure and Function
- 06:38Conclusion
Here we describe a step-by-step protocol of surgical aorta debanding in the well-established mice model of aortic-constriction. This procedure not only allows studying the mechanisms underlying the left ventricular reverse remodeling and regression of hypertrophy but also to test novel therapeutic options that might accelerate myocardial recovery.
