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Porcine Model of Infrarenal Abdominal Aortic Aneurysm
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JoVE Journal Medicina
Porcine Model of Infrarenal Abdominal Aortic Aneurysm

Porcine Model of Infrarenal Abdominal Aortic Aneurysm

DOI:
10.3791/60169-v

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11:13 min

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November 21, 2019

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, , , , , , , , , , ,
1Department of Surgery,University of Virginia School of Medicine, 2Department of Surgery,Ochsner Medical Center, 3Department of Surgery,University of Florida, 4The Robert M. Berne Cardiovascular Research Center,University of Virginia School of Medicine

Capitoli

  • 00:04Titolo
  • 00:44Surgical Technique
  • 09:35Results: Representative Infrarenal Abdominal Aortic Aneurysm (AAA) Analyses
  • 10:36Conclusion

Summary

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This novel model creates robust infrarenal abdominal aortic aneurysms in swine using a combination of balloon angioplasty, elastase/collagenase perfusion, topical elastase application, and oral compound β-aminopropionitrile administration, which interferes with collagen cross-linking.

Tags

Keywords: Porcine ModelInfrarenal Abdominal Aortic AneurysmElastaseBAPNAbdominal Aortic AneurysmSurgical ProcedureLaparotomyRetroperitoneumAortic DissectionAortic DiameterCaudal Mesenteric Artery

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