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通过化学测量方法，从活体共聚焦拉曼光谱中解决水、蛋白质和脂质
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Chimica
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JoVE Journal Chimica
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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通过化学测量方法，从活体共聚焦拉曼光谱中解决水、蛋白质和脂质

DOI:
10.3791/60186-v

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09:32 min

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September 26, 2019

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, , , , , , ,
1Procter and Gamble,Beijing Innovative center, 2Procter and Gamble,Mason Business Center, 3Department of Dermatology,Beijing Children’s Hospital, 4Chinese Academy of Inspection and Quarantine

Capitoli

  • 00:04Titolo
  • 01:22Collection of In Vivo Confocal Raman Spectra from Human Subjects with Atopic Dermatitis
  • 02:10Removal of the Out-of-skin Spectra
  • 04:38Removing the Outlier Spectra with the Room Light Effect
  • 06:16Selection of the Number of Components in MCR Decomposition Analysis
  • 07:35Results: Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum
  • 08:56Conclusion

Summary

Traduzione automatica

Traduzione automatica

在这里，我们提出了一个方案，从临床研究中从人类受试者收集共聚焦拉曼光谱，结合化学方法去除光谱异常值和随后提取关键特征。

Tags

In Vivo Confocal Raman SpectroscopyStratum CorneumWaterProteinsLipidsChemometricsData PreprocessingBaseline CorrectionOutlier DetectionDepth Profiling

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