Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Chemistry / A Direct, Regioselective and Atom-Economical…
JoVE Journal
Chemistry

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Chemistry
A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
 

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Article DOI: 10.3791/60201-v • 07:30 min • January 21st, 2020
January 21st, 2020 •
1, 1, 1, 1, 2, 1
1Dipartimento di Scienza e Alta Tecnologia, Università degli Studi dell'Insubria, 2Department of Chemistry and Biochemistry, University of Oklahoma, Stephenson Life Sciences Research Center

Capitoli

Riepilogo
Automatic Translation

3-Aroyl-N-hydroxy-5-nitroindoles were synthesized by cycloaddition of 4-nitronitrosobenzene with a conjugated terminal alkynone in a one-step thermal procedure. Preparation of the nitrosoarene and of the alkynones were adequately reported and respectively through oxidation procedures on the corresponding aniline and on the alkynol.

Tags

Keywords: 3-aroyl-N-hydroxy-5-nitroindoles Cycloaddition 4-nitronitrosobenzene Alkynonones N-hydroxyindoles Regioselective Synthesis Atom-economical Antibiotics Antinociceptics Antidiabetes Anticancer Drugs Nitrosamines Alkynes 1-phenyl-2-propyne-1-one Jones Reagent 4-nitroaniline Potassium Peroxy Monosulfate
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter