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分散（Ex Vivo）的毛骨球模型，去除了除位肌肉，用于在膀胱填充期间直接进入苏布罗氦

JoVE Journal
Medicina

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JoVE Journal Medicina

A Decentralized (Ex Vivo) Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

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分散（Ex Vivo）的毛骨球模型，去除了除位肌肉，用于在膀胱填充期间直接进入苏布罗氦

DOI:

10.3791/60344-v

•

06:36 min

•

November 28, 2019

•

Leonie Durnin², Robert D. Corrigan, Kenton M. Sanders, Violeta N. Mutafova-Yambolieva

¹Department of Physiology and Cell Biology,University of Nevada Reno School of Medicine, ²Charles River Laboratories Inc.

Capitoli

00:05Titolo
00:40Detrusor-Free Bladder Preparation Dissection
02:41Denuded Bladder Preparation Filling and Mediator Detection
03:40Results: Representative Denuded Murine Bladder Preparation Assessment
05:44Conclusion

Summary

Traduzione automatica

无分泌物的膀胱模型允许直接进入亚尿层，以研究在尿液储存和排空期间调节亚尿层/拉米纳尿体中生物活性介质可用性的本地机制。制备与填充完整膀胱非常相似，允许在无系统影响的情况下进行压力体积研究。

Tags

Keywords: Decentralized Bladder Model Detrusor Muscle Removal Suburothelium Bladder Filling Urothelial Mediators Signaling Mechanisms Bladder Excitability Murine Bladder Specimen Dissection Oxygenated KBS Detrusor Muscle Layer Bladder Mucosa Catheter Insertion Organ Dish

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