È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
1Medical Physics Unit,Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 2Oncology Pharmacy,Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 3Nuclear Medicine Unit,Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, 4Radiation Research Unit,Istituto Europeo di Oncologia (IEO) IRCCS, Milano, Italy, 5Medical Physics Unit,Istituto Europeo di Oncologia (IEO) IRCCS, Milano, Italy
Capitoli
- 00:04Introduction
- 01:24Pre-Infusion Imaging: Transmission and Blank Image Acquisition
- 02:35Post-Infusion Image Acquisition: Planar Image
- 03:21Post-Infusion Image Acquisition: 3D SPECT/CT
- 03:51Image Analysis
- 04:58Blood Sample Measurements and Dosimetry Evaluation
- 05:50Hybrid 2D+3D SCPET/CT Image Analysis
- 06:21Adult Phantom Creation and Red Marrow Evaluation
- 07:50Results: Representative Comparison of 2D, Hybrid 2D+3D, and 3D SPECT/CT Methods for Transient Intestine Uptake Overlap on Kidneys
- 08:35Conclusion
Cette méthode estime la dose absorbée de différentes structures pour le peptide-récepteur-radionucléide-thérapie (PRRT) avec la possibilité d’éviter le chevauchement d’organe sur les projections 2D. Les images planaires en série du corps entier permettent d’estimer les doses moyennes absorbées le long du corps tout entier, tandis que l’approche hybride, combinant des images planaires et l’image 3D-SPECT/CT, surmonte les limites du chevauchement de la structure.
