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Repeated Orotracheal Intubation in Mice
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JoVE Journal Medicina
Repeated Orotracheal Intubation in Mice

Repeated Orotracheal Intubation in Mice

DOI:
10.3791/60844-v

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06:26 min

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March 27, 2020

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, ,
1Department of Veterinary Biosciences,The Ohio State University

Capitoli

  • 00:04Introduction
  • 01:05Procedure Preparation
  • 02:21Intubation
  • 04:09Recovery
  • 04:56Results: Representative Serial Monitoring of Baseline Pulmonary Function
  • 05:43Conclusion

Summary

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The goal of this article is to describe a refined method of intubation of the laboratory mouse. The method is noninvasive and, therefore, ideal for studies that require serial monitoring of respiratory function and/or instillation of treatments into the lung.

Tags

Repeated Orotracheal IntubationLung Function MeasurementMiceChronic Lung DiseasesAsthmaCOPDEmphysemaPulmonary FibrosisAnesthesiaIntubation PlatformCannulaTail RetractionDepilatory CreamTongue RetractionTrachea Palpation

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