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Induction of Leptomeningeal Cells Modification Via Intracisternal Injection
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Capitoli
- 00:04Introduction
- 01:07Preparation of the Injection System
- 02:54Intracisternal Injection
- 03:55Results: Specific Labelling of Leptomeningeal Cells via Intracisternal Injection of Endoxifen
- 05:07Conclusion
We describe an intracisternal injection that employs a needle bent at the tip that can be stabilized to the skull, thus eliminating the risk of damage to the underlying parenchyma. The approach can be used for genetic fate mapping and manipulations of leptomeningeal cells and for tracking cerebrospinal fluid movement.
