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Capitoli
- 00:05Introduction
- 01:22Animal Preparation and Dissection
- 03:21Right Renal Artery Stenosis
- 04:42Tissue Harvest
- 06:04Results: Renin Expression after Renal Artery Stenosis
- 07:52Conclusion
A modified 2 kidney 1 clip (2K1C) Goldblatt mouse model was developed using polyurethane tubing to initiate renal artery stenosis, inducing an increase in renin expression and kidney injury. Here, we describe a detailed procedure of preparing and placing the cuff onto the renal artery to generate a reproducible and consistent 2K1C mouse model.
