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代谢通路信息 GWAS 分析的路径关联研究工具
JoVE Journal
Genetica
This content is Free Access.
JoVE Journal Genetica
A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
DOI:

05:01 min

July 01, 2020

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Capitoli

  • 00:05Introduction
  • 00:32Genome-Wide Association Study (GWAS) Data Loading
  • 00:57Load Linkage Disequilibrium (LD) Data Loading
  • 01:26Single Nucleotide Polymorphism (SNP) Assignment
  • 01:56Significant Pathway Discovery
  • 02:35Rugplot Visualization
  • 03:21Results: Representative GWAS Analyses of Metabolic Pathway Information
  • 04:21Conclusion

Summary

Traduzione automatica

通过运行路径关联研究工具 (PAST),无论是通过闪亮应用还是通过 R 控制台,研究人员可以通过调查所涉及的代谢途径,更深入地了解其全基因组关联研究 (GWAS) 结果的生物学意义。

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