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在穆林模型中缺血再灌注损伤后干细胞的心肌内传递延迟

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Medicina

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JoVE Journal Medicina

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

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在穆林模型中缺血再灌注损伤后干细胞的心肌内传递延迟

DOI:

10.3791/61546-v

•

07:50 min

•

September 03, 2020

•

Michaela Olthoff, Federico Franchi, Karen M. Peterson, Ramasamy Paulmurugan, Martin Rodriguez-Porcel

¹Department of Cardiovascular Medicine,Mayo Clinic, ²Department of Radiology and Molecular Imaging Program at Stanford (MIPS),Stanford University School of Medicine

Capitoli

00:04Introduction
00:54Preparation and Intubation
02:10Ischemia Reperfusion Injury
04:15Mouse Mesenchymal Stem Cell Delivery
06:07Results: Heart Function after Ischemic Injury
07:05Conclusion

Summary

Traduzione automatica

干细胞作为心肌损伤患者的潜在治疗方法不断被研究，然而，干细胞在损伤组织中生存能力的降低和保留会影响其长期疗效。在这份手稿中，我们描述了一种替代干细胞传递方法，该模型采用缺血再灌注损伤的穆林模型。

Tags

AI-assisted Writing Stem Cell Therapy Ischemia-reperfusion Injury Delayed Cell Delivery Surgical Procedure Murine Model

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