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Natrium taurocholat induceret svær akut pancreatitis i C57BL/6 Mus
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JoVE Journal Medicina
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Natrium taurocholat induceret svær akut pancreatitis i C57BL/6 Mus

DOI:
10.3791/61547-v

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06:35 min

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June 28, 2021

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, , , ,
1Discipline of Clinical Emergencies, Department of Clinical Medicine, HCFMUSP / LIM 51,University of São Paulo Medical School

Capitoli

  • 00:04Introduction
  • 01:07Laparotomy and Exposing the Pancreas
  • 02:17Severe Acute Pancreatitis Induction
  • 03:30Methods for Analysis
  • 05:13Results: Analysis of Histological and Serological Changes after Induction of Acute Pancreatitis
  • 06:00Conclusion

Summary

Traduzione automatica

Traduzione automatica

Dyremodeller for alvorlig akut pancreatitis muliggør undersøgelse af patofysiologiske ændringer i den indledende fase, hvilket letter observation af udviklingen af inflammatoriske begivenheder. Her giver vi en protokol for induktion af svær akut galde pancreatitis ved retrograd infusion af natrium taurocholat i bugspytkirtlen kanalen af bedøvet C57BL/6 mus.

Tags

Keywords: Acute PancreatitisC57BL/6 MiceSodium TaurocholateBiliary PancreatitisInflammatory ResponsePharmacological InterventionLaparotomyCommon Bile DuctDuodenumInfusionAnimal Model

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