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1Cardiovascular Research Institute for Intractable Disease, College of Medicine,The Catholic University of Korea, 2Division of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine,The Catholic University of Korea, 3Division of Cardiology, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine,The Catholic University of Korea
Capitoli
- 00:05Introduction
- 01:49Preparation of MSCs and Injectable Gelatin Hydrogels
- 03:38In Situ MSC-loading and Three-dimensional in Vitro Culture
- 04:29Induction of Myocardial Infarction in Mice
- 05:44Intramyocardial Transplantation of MSC-loading GH Hydrogels
- 06:37Results: Improving Stem Cell Retention and Engraftment with Injectable Hydrogels
- 08:31Conclusion
Stamcellebaseret terapi har vist sig som en effektiv strategi til at reparere skadet hjertevæv efter myokardieinfarkt. Vi leverer en optimal in vivo ansøgning om stamcelletransplantation ved hjælp af gelatine hydrogels, der er i stand til at være enzymatisk krydsbundet.
Tags
Keywords:
Mesenchymal Stem CellsMSCsInjectable HydrogelsIntramyocardial TransplantationMyocardial InfarctionMurine ModelCell RetentionCell SurvivalGrowth FactorsGenetic MaterialsDrugsIn Vitro ExperimentIn Vivo ExperimentCell CultureCell SuspensionTrypsinTrypan BlueCell CountingGH Conjugate SolutionHydrogen PeroxideDual Syringe
