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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
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Capitoli
- 00:04Introduction
- 00:38Dissection Setup
- 01:07Tissue Dissection
- 02:15Anterior Segments Setup in Organ Culture Dishes
- 03:58Starting Anterior Segment Organ Culture
- 04:30Open Globe Injury Induction
- 05:29Results: Corneal Integrity and Intraocular Pressure Assessment after Open Globe Injury
- 06:53Conclusion
Open globe eye injuries may go untreated for multiple days in rural or military-relevant scenarios, resulting in blindness. Therapeutics are needed to minimize loss of vision. Here, we detail an organ culture open globe injury model. With this model, potential therapeutics for stabilizing these injuries can be properly evaluated.
