Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Bioengineering / A Large Animal Model for Pulmonary Hypertension…
JoVE Journal
Bioengineering

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Bioengineering
A Large Animal Model for Pulmonary Hypertension and Right Ventricular Failure
 

A Large Animal Model for Pulmonary Hypertension and Right Ventricular Failure: Left Pulmonary Artery Ligation and Progressive Main Pulmonary Artery Banding in Sheep

Article DOI: 10.3791/62694-v • 07:02 min • July 15th, 2021
July 15th, 2021 •
1, 1, 1, 1, 1, 1, 5, 1, 3, 2, 4, 1,6
1Department of Thoracic Surgery, Vanderbilt University Medical Center, 2Department of Biomedical Engineering, Carnegie Mellon University, 3Department of Pediatrics, Columbia University Medical Center, Columbia University Irving Medical Center, 4Department of Medicine, Columbia University Medical Center, Columbia University Irving Medical Center, 5Department of Anesthesiology, Vanderbilt University Medical Center, 6Department of Biomedical Engineering, Vanderbilt University

Capitoli

Riepilogo
Automatic Translation

This manuscript describes the surgical technique and experimental approach to develop severe right ventricular pressure overload to model their adaptive and maladaptive phenotypes.

Tags

Keywords: Pulmonary Hypertension Right Ventricular Failure Large Animal Model Left Pulmonary Artery Ligation Pulmonary Artery Banding RV Adaptation RV-targeted Therapeutics Surgical Procedure Sheep Model Thoracotomy Pulmonary Artery Dissection Vascular Occluder Right Ventricular Pressure Line
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter