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Bioengineering

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JoVE Journal Bioengineering
Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
 

Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants

Article DOI: 10.3791/62781-v • 04:16 min • August 5th, 2021
August 5th, 2021 •
1,2, 1,2, 1,2,3, 1,2,3, 1,2,4, 1,2,4
1Cell Therapy and Tissue Engineering Group, Research Institute on Health Sciences (IUNICS), University of the Balearic Islands, 2Health Research Institute of the Balearic Islands (IdISBa), 3Fundació Banc de Sang i Teixits de les Illes Balears (FBSTIB), 4Department of Fundamental Biology and Health Sciences, University of the Balearic Islands

Capitoli

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Automatic Translation

Here, we present a method for the isolation of Extracellular Vesicles (EVs) derived from the platelet lysates (PL) and their use for coating titanium (Ti) implant surfaces. We describe the drop casting coating method, the EVs release profile from the surfaces, and in vitro biocompatibility of EVs coated Ti surfaces.

Tags

Keywords: Titanium Implants Extracellular Vesicles Surface Functionalization Drop Casting Bone Regeneration Nanoparticle Tracking Analysis Sodium Hydroxide Nitric Acid Vacuum Drying
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