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Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice
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Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice

Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice

DOI:
10.3791/63257-v

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08:28 min

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January 19, 2022

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, , , , , , , , ,
1Department of Cardiology, Union Hospital, Tongji Medical College,Huazhong University of Science and Technology

Capitoli

  • 00:04Introduction
  • 00:35Preoperative Preparation
  • 03:10Thoracotomy
  • 04:36LAD Ligation
  • 06:05Reperfusion
  • 07:13Results: A Simple and Reproductive Murine Model for Myocardial Ischemia-Reperfusion Injury and Myocardial Infarction
  • 07:48Conclusion

Summary

Traduzione automatica

Traduzione automatica

Here we describe a simple and reproducible method that can induce myocardial infarction or myocardial ischemia-reperfusion injury in mice by precision ligation of the left anterior descending coronary artery through micromanipulation.

Tags

Keywords: Myocardial InfarctionMyocardial Ischemia-reperfusion InjuryMouse ModelLeft Anterior Descending Coronary Artery LigationSurgical ProcedureIntubationMechanical VentilationECG Monitoring

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