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小鼠右冠状动脉永久结扎诱导的右心室性心肌梗死的生成与表征

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Medicina

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JoVE Journal Medicina

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

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小鼠右冠状动脉永久结扎诱导的右心室性心肌梗死的生成与表征

DOI:

10.3791/63508-v

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10:18 min

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February 01, 2022

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Ruoxi Liao, Mingyuan He, Donghong Hu, Chengzheng Gong, Huiying Du, Hairuo Lin, Huijun Sun

¹The First Clinical College of Dalian Medical University, ²Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital,Southern Medical University, ³College of Pharmacy,Dalian Medical University

Capitoli

00:04Introduction
00:54Preparation for Surgery
01:37Permanent Ligation of the Right Coronary Artery
03:03Echocardiographic Assessment of the RV (Right Ventricle) Function After Surgery
05:25Invasive Measurements of RV Hemodynamic
06:43Coronary Vascular Cast Using a Vascular Casting Agent
07:49Results: Electrocardiography, Echocardiography and Histological Assessment After Right Coronary Artery Ligation
09:48Conclusion

Summary

Traduzione automatica

右心室和左心室之间有几个区别。然而，右心室梗死（RVI）的病理生理学尚未明确。在本方案中，引入了一种用于生成RVI小鼠模型的可重复方法，该方法可以提供解释RVI机制的方法。

Tags

Right Ventricular Infarction Right Coronary Artery Ligation Mouse Model Myocardial Infarction Ischemia ECG Surgical Procedure Ultrasound Imaging

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