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藏族小型猪射血分数保留的心力衰竭手术模型

JoVE Journal
Medicina

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JoVE Journal Medicina

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs

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藏族小型猪射血分数保留的心力衰竭手术模型

DOI:

10.3791/63526-v

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07:09 min

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February 18, 2022

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Xiaohui Li*^1,2, Weijiang Tan*^1,3, Xiang Li*¹, Shuang Zheng*¹, Xiaoshen Zhang, Honghua Chen, Zhanhong Pan, Caiyi Zhu, Feng Hua Yang

¹Guangdong Laboratory Animals Monitoring Institute, ²Department of Cardiovascular Surgery,the First Affiliated Hospital, Jinan University, ³College of Veterinary Medicine,South China Agricultural University

Capitoli

00:04Introduction
01:23Sedation, Tracheal Intubation, and Vein Cannulation
02:10Surgical Procedure
03:41Transthoracic Echocardiography
04:51Results: Heart Failure with Preserved Ejection Fraction
06:51Conclusion

Summary

Traduzione automatica

本方案描述了使用降主动脉收缩建立射血分数保留的心力衰竭迷你猪模型的分步程序。还介绍了评估该疾病模型的心脏形态学、组织学和功能的方法。

Tags

Keywords: Heart Failure HFpEF Tibetan Minipigs Surgical Model Aortic Constriction Pressure Overload Echocardiography Animal Care Surgical Technique Anesthesia Monitoring

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