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Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
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Capitoli
- 00:04Introduction
- 00:50Infection of C. elegans with N. Parisiito Yield Immune-Primed Offspring
- 03:30Testing Inherited Immunity to N. Parisii di C. elegans and Analysis of DY96-Stained Worms to Assess Infection Status
- 06:10Results: Study of Inherited Immunity in Genetically Tractable Worm Model
- 08:32Conclusion
The infection of Caenorhabditis elegans by the microsporidian parasite Nematocida parisii enables the worms to produce offspring that are highly resistant to the same pathogen. This is an example of inherited immunity, a poorly understood epigenetic phenomenon. The present protocol describes the study of inherited immunity in a genetically tractable worm model.
