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Quantificação total versus sub-regional da carga amilóide-beta nas seções cerebrais do rato
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1Henry E. Riggs School of Applied Life Sciences,Keck Graduate Institute, 2Crean College of Health and Behavioral Sciences,Chapman University, 3Keck Science Department,Claremont McKenna College, 4Department of Biomedical and Pharmaceutical Sciences, School of Pharmacy,Chapman University, 5Department of Neurology,University of California, Irvine
Capitoli
- 00:05Introduction
- 00:42Full-Region of Interest (ROI) Analysis
- 03:28Sub-Region of Interest (ROI) Analysis
- 05:19Results: Impact of Size of ROI on Aβ-Positive Area Quantification in the APP/PS1 Transgenic Mouse of Alzheimer’s Disease
- 06:50Conclusion
O presente protocolo descreve e compara o procedimento para realizar uma análise de interesse de região completa ou sub-região de seções cerebrais de camundongos sagitos para quantificar a carga amilóide-beta no modelo de camundongo transgênico APP/PS1 da doença de Alzheimer.
