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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
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JoVE Journal Medicina
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

DOI:
10.3791/64066-v

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11:09 min

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December 16, 2022

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, , , , , ,
1CNR Institute of Clinical Physiology, 2Sant’Anna School of Advanced Studies, 3Fondazione Regione Toscana/CNR “G. Monasterio”

Capitoli

  • 00:05Introduction
  • 01:31Animal Preparation for Positron Emission Tomography (PET)/Computed Tomography (CT) Imaging
  • 02:08PET Tracer Dose Preparation
  • 02:55CT Contrast Agent Preparation
  • 03:35CT Scans
  • 04:34PET Cardiac Analysis
  • 06:21Cine-CT Cardiac Analysis
  • 08:46Results: Morphofunctional and Metabolic Evaluation of the Heart
  • 10:19Conclusion

Summary

Traduzione automatica

Traduzione automatica

Here, we present an experimental imaging protocol for the quantification of cardiac function and morphology using high-resolution positron emission tomography/computed tomography for small animals. Both mice and rats are considered, discussing the different requirements of computed tomography contrast agents for the two species.

Tags

Keywords: Cardiac PET/CTSmall Animal ImagingMyocardial InfarctionCardiometabolic DiseasesCardiac MetabolismCardiac FunctionF-18 FDGIomeprolCaudal Vein CannulationBlood SamplingAnesthesiaTemperature MonitoringRespiration MonitoringMotion Artifacts

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