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A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model
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Biologia
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JoVE Journal Biologia
A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

DOI:
10.3791/64173-v

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05:14 min

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November 18, 2022

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, , , ,
1Department of Physiology and Pathophysiology, School of Basic Medical Sciences; Key Laboratory of Molecular Cardiovascular Science, Ministry of Education,Peking University, 2Department of Vascular and Endovascular Surgery, the First Medical Centre,Chinese PLA General Hospital

Capitoli

  • 00:05Introduction
  • 00:55Preparation and Surgical Procedure
  • 03:05Harvesting for Imaging of Aortas and Evaluation of the Degradation of the Elastic Fibers
  • 03:47Results: Pathological Features and Molecular Mechanisms of Calcium Phosphate-Induced Abdominal Aortic Aneurysm
  • 04:15Conclusion

Summary

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Traduzione automatica

This protocol describes a calcium phosphate-induced abdominal aortic aneurysm (AAA) mouse model to study the pathological features and molecular mechanisms of AAAs.

Tags

Keywords: Calcium PhosphateAbdominal Aortic AneurysmMouse ModelInfrarenal AortaAdventitiaCalcium ChloridePBSSutureSurgeryAnesthesiaMonitoring

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