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斑马鱼幼虫作为评估潜在放射增敏剂或保护剂的模型

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Zebrafish Larvae as a Model to Evaluate Potential Radiosensitizers or Protectors

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斑马鱼幼虫作为评估潜在放射增敏剂或保护剂的模型

DOI:

10.3791/64233-v

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04:53 min

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August 25, 2022

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Amlan P. Mohapatra*^1,3, Deepti Parida*^1,3, Debasish Mohapatra⁴, Usharani Nayak³, Rajeeb K. Swain, Shantibhusan Senapati

¹Tumor microenvironment and animal models lab,Institute of Life Sciences, ²Vascular Biology lab,Institute of Life Sciences, ³Regional Centre for Biotechnology, ⁴School of Biotechnology,KIIT University

Capitoli

00:04Introduction
00:57Monitoring Embryos and Selection for Radiation Experiments
01:28X‐Ray Irradiation
02:38Data Collection, Imaging, and Analysis
03:17Results: Effect of Different Doses of X‐Ray Irradiation on 6 hpf Zebrafish Embryos
04:23Conclusion

Summary

Traduzione automatica

斑马鱼最近被用作验证潜在辐射改性剂的模型。本方案描述了使用斑马鱼胚胎进行基于辐射的筛选实验的详细步骤以及一些观察方法来评估不同治疗和辐射的效果。

Tags

Zebrafish Larvae Radiation Screening Radiosensitizers Radioprotectors Radiation-based Experiments High-throughput Drug Screening Radiobiology Radiotherapy X-ray Irradiation Embryo Staging Observational Approaches Survival Hatching Efficiency Developmental Stages Phenotypic Changes

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