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Isolatie van gentherapievectoren van de volgende generatie door middel van engineering, barcoding en screening van adeno-geassocieerde virus (AAV) capsid-varianten
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1Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty,University of Heidelberg, 2BioQuant Center, BQ0030,University of Heidelberg, 3Cluster of Excellence CellNetworks, 4German Center for Infection Research (DZIF), 5German Center for Cardiovascular Research (DZHK)
Capitoli
- 00:05Introduction
- 01:16Analysis of the AAV Viral Library (In Vitro) by NGS
- 03:42Analysis of AAV Viral Library (In Vivo) by NGS
- 07:08Results: Peptide Display AAV Capsid Engineering and Barcoded AAV Library Screening for Isolation of Next-Generation Gene Therapy Vectors
- 08:36Conclusion
