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机械通气仔猪肾小球滤过率的透皮测量

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Medicina

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JoVE Journal Medicina

Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets

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机械通气仔猪肾小球滤过率的透皮测量

DOI:

10.3791/64413-v

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07:41 min

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September 13, 2022

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Mina S. Fanous*¹, Jeremiah M. Afolabi*¹, Olugbenga S. Michael, Olufunke O. Falayi, Samson A. Iwhiwhu, Adebowale Adebiyi

¹Department of Physiology,College of Medicine University of Tennessee Health Science Center

Capitoli

00:05Introduction
01:13Experiment Group: Cecal Ligation and Perforation (CLP)
02:35Transdermal GFR Device Setup
03:49FITC-Sinistrin Preparation, Injection, and Transdermal GFR Recording
04:43GFR Measurement
05:47Results: Analysis of GFR Using Transdermal GFR Device
07:02Conclusion

Summary

Traduzione automatica

肾小球滤过率（GFR）是评估肾功能的理想标志物。然而，使用菊粉注射液和连续血液和尿液分析的标准测量方法是不切实际的。本文描述了一种经皮测量仔猪GFR的实用方法。

Tags

Keywords: Transdermal GFR Measurement Kidney Function Swine Model Xenotransplantation Piglets Cecal Ligation Tracheostomy Vessel Cannulation Real-time Assessment Non-invasive

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