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多形性胶质母细胞瘤的转化原位模型
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JoVE Journal Ricerca sul cancro
Translational Orthotopic Models of Glioblastoma Multiforme
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多形性胶质母细胞瘤的转化原位模型

DOI:
10.3791/64482-v

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07:37 min

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February 17, 2023

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, ,
1Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research,National Cancer Institute

Capitoli

  • 00:04Introduction
  • 01:23Surgical Area and Mouse Preparation
  • 03:34Cell Injection, Needle Removal, and Wound Closure
  • 05:53Results: Assessment of an Orthotopic Mouse Tumor Model for Human Glioblastoma Multiforme
  • 06:55Conclusion

Summary

Traduzione automatica

Traduzione automatica

在这里，我们描述了GBM的临床前原位小鼠模型，该模型是通过颅内注射源自基因工程小鼠模型肿瘤的细胞而建立的。该模型显示了人类GBM的疾病特征。对于转化研究，通过 体内 MRI和组织病理学跟踪小鼠脑肿瘤。

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