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兔子缺血和再灌注损伤模型

JoVE Journal
Medicina

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JoVE Journal Medicina

Model of Ischemia and Reperfusion Injury in Rabbits

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兔子缺血和再灌注损伤模型

DOI:

10.3791/64752-v

•

06:11 min

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November 03, 2023

•

Victor S. Alemany*¹, Dominic P. Recco*¹, Sitaram M. Emani, Pedro J. del Nido, James D. McCully

¹Department of Cardiac Surgery, Boston Children’s Hospital,Harvard Medical School

Capitoli

00:00Introduction
00:52Mini‐Thoracotomy (Survival)
02:25LAD Artery Isolation and Incision Closure
03:23Midline Sternotomy (Non‐Survival) and LAD Artery Isolation
04:18Coronary Artery Occlusion and Ischemia Confirmation
04:52Results: Analysis of Acute Regional Myocardial Ischemia in a Rabbit Model
05:29Conclusion

Summary

Traduzione automatica

本研究展示了兔子急性局部心肌缺血和再灌注损伤的高度可重复动物模型，使用左侧微型开胸术治疗生存病例或中线胸骨切开术治疗非生存病例。

Tags

Keywords: Rabbit Model Ischemia-reperfusion Injury LAD Artery Mini-thoracotomy Survival Study Pericardial Sac 3-0 Polypropylene Suture Polyglactin 910 Stitches Low Technical Demand

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