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Rastreamento de limiar elétrico de circuito fechado em tempo fechado de código aberto para pesquisa translacional da dor
This content is Free Access.
1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience,University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science,University of Bristol, 4Department of Aerospace Engineering,University of Bristol, 5Research Computing,University of Bristol
Capitoli
- 00:04Introduction
- 01:29Assembly of the Recording and Stimulating Apparatus
- 03:27Software Setup and Identification and Phenotyping of Peripheral Neurons
- 05:43Latency and Electrical Threshold Tracking
- 08:00Results: Electrical Threshold Tracking of Single‐Neuron Action Potentials
- 09:43Conclusion
APTrack é um plugin de software desenvolvido para a plataforma Open Ephys que permite a visualização de dados em tempo real e o rastreamento do limiar elétrico em malha fechada de potenciais de ação neuronais. Nós usamos isso com sucesso em microneurografia para nociceptores de fibra C humana e nociceptores de fibra C e fibra Aδ de camundongo.
Tags
Open-sourceReal-timeClosed-loopElectrical Threshold TrackingTranslational Pain ResearchNociceptor SensitizationAutomated Electrical Threshold TrackingNociceptor ExcitabilityBiomarkerAP TrackElectrophysiologyOptogeneticsAcquisition BoardIO BoardIntan RHD Recording HeadstagePulse PalConstant Current StimulatorStepper Motor Control BoardCustom Mounting BracketBarrel Adapter
