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Quantifying Locomotor Dysfunction in Spinal Cord Injury Mice Using MouseWalker

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MouseWalkerを用いた脊髄損傷マウスモデルにおける自発運動機能障害の定量化

JoVE Journal
Neuroscienze

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JoVE Journal Neuroscienze

Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury

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MouseWalkerを用いた脊髄損傷マウスモデルにおける自発運動機能障害の定量化

Quantifying Locomotor Dysfunction in Spinal Cord Injury Mice Using MouseWalker

DOI:

10.3791/65207-v

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02:40 min

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March 24, 2023

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Ana Filipa Isidro, Alexandra M. Medeiros, Isaura Martins, Dalila Neves-Silva, Leonor Saúde³, César S. Mendes

¹Instituto de Medicina Molecular João Lobo Antunes,Faculdade de Medicina da Universidade de Lisboa, ²iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM,Universidade Nova de Lisboa, ³Instituto de Histologia e Biologia do Desenvolvimento,Faculdade de Medicina da Universidade de Lisboa

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Keywords: Mouse Walker Spinal Cord Injury Locomotor Dysfunction Quantitative Analysis Motor Activity Coordination Open Source Tools Gait Limb Coordination Locomotor Behavior Free-walking Behavior Frustrated Total Internal Reflection

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MouseWalkerを用いた脊髄損傷マウスモデルにおける自発運動機能障害の定量化

マウスウォーカー(MW)装置のセットアップ

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マウスウォーカー(MW)ビデオトラッキングとキネマティックデータ解析

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