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Transcriptome Profiling for High-Throughput Drug Screening

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Kosteneffizientes transkriptomisches Wirkstoff-Screening

JoVE Journal
Biologia

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JoVE Journal Biologia

Cost-Efficient Transcriptomic-Based Drug Screening

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Kosteneffizientes transkriptomisches Wirkstoff-Screening

Transcriptome Profiling for High-Throughput Drug Screening

DOI:

10.3791/65930-v

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01:10 min

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February 23, 2024

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Jacqueline Leidner², Heidi Theis, Michael Kraut, Alice Ragogna, Marc Beyer^3,4, Joachim Schultze^2,3, Jonas Schulte-Schrepping², Caterina Carraro², Lorenzo Bonaguro²

¹Systems Medicine,German Center for Neurodegenerative Diseases (DZNE) eV., ²Genomics & Immunoregulation, LIMES Institute,University of Bonn, ³PRECISE Platform for Single Cell Genomics and Epigenomics,DZNE and University of Bonn, ⁴Immunogenomics & Neurodegeneration,German Center for Neurodegenerative Diseases (DZNE) eV.

Tags

Keywords: Transcriptomics Drug Screening Cost-effective Mini-bulk Transcriptomics Cellular Programs Drug Targets Unbiased Drug Screening Library Production Sequencing Depth Miniaturized Perturbation Cultures Time-independent High-throughput

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