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一个线虫多巴胺神经元退化含量的应用验证潜在的帕金森氏症基因
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Biologia
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JoVE Journal Biologia
Application of a C. elegans Dopamine Neuron Degeneration Assay for the Validation of Potential Parkinson’s Disease Genes
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一个线虫多巴胺神经元退化含量的应用验证潜在的帕金森氏症基因

DOI:
10.3791/835-v

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08:42 min

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July 18, 2008

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, , , , ,
1Department of Biological Sciences,University of Alabama

Capitoli

  • 00:26Introduction
  • 01:44Performing Genetic Crosses for Dopamine Neurodegeneration Analysis
  • 03:51Performing Dopaminergic Neuron Analysis
  • 07:49Conclusion

Summary

Traduzione automatica

Traduzione automatica

该视频演示如何使用线虫作为帕金森病模型的多巴胺能神经元的神经退行性疾病，以评估。此外，遗传屏幕是用来识别，要么提高变性或神经因素。

Tags

C. ElegansDopamine Neuron Degeneration AssayParkinson’s Disease GenesDiagnosisTreatmentSusceptibility FactorsCandidate GenesPolymorphismsProteinsAnimal Model SystemCaenorhabditis ElegansDopamine NeuronsAlpha-synucleinNeurodegenerationGFPDA Transporter Promoter (Pdat-1)TorsinARNAi

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