Erin E. Kershaw Division of Endocrinology and Metabolism University of Pittsburgh Biography Publications Institution JoVE Articles Erin E. Kershaw has not added a biography. If you are Erin E. Kershaw and would like to personalize this page please email our Author Liaison for assistance. Publications Role of Cardiorespiratory Fitness and Mitochondrial Oxidative Capacity in Reduced Walk Speed of Older Adults with Diabetes Diabetes. Mar, 2024 | Pubmed ID: 38551899 Percutaneous Biopsies of Skeletal Muscle and Adipose Tissue in Individuals Older Than 70: Methods and Outcomes in the Study of Muscle, Mobility and Aging (SOMMA) GeroScience. Jun, 2024 | Pubmed ID: 38315316 Association Between Age at Menarche and Cardiometabolic Risk Among Samoan Adults American Journal of Human Biology : the Official Journal of the Human Biology Council. Jan, 2024 | Pubmed ID: 37668413 Acute Activation of Adipocyte Lipolysis Reveals Dynamic Lipid Remodeling of the Hepatic Lipidome Journal of Lipid Research. Feb, 2024 | Pubmed ID: 37640283 Medical Management of Hypertriglyceridemia in Pancreatitis Current Opinion in Gastroenterology. Sep, 2023 | Pubmed ID: 37421386 Leveraging Inter-individual Transcriptional Correlation Structure to Infer Discrete Signaling Mechanisms Across Metabolic Tissues BioRxiv : the Preprint Server for Biology. Oct, 2023 | Pubmed ID: 37214953 Evinacumab in Severe Hypertriglyceridemia with or Without Lipoprotein Lipase Pathway Mutations: a Phase 2 Randomized Trial Nature Medicine. Mar, 2023 | Pubmed ID: 36879129 Multivariate Analysis of a Missense Variant in CREBRF Reveals Associations with Measures of Adiposity in People of Polynesian Ancestries Genetic Epidemiology. Feb, 2023 | Pubmed ID: 36352773 A Stop-gain Variant in is Associated with Atherogenic Lipid Profiles HGG Advances. Jan, 2023 | Pubmed ID: 36340932 The Protective Effect of Rs373863828 on Type 2 Diabetes Does Not Operate Through a Body Composition Pathway in Adult Samoans Obesity (Silver Spring, Md.). Dec, 2022 | Pubmed ID: 36284436 Effect of Physical Activity in a Weight Loss Program on Circulating Total ANGPTL8 Concentrations in Northern Americans with Obesity: A Prospective Randomized Controlled Trial Nutrition, Metabolism, and Cardiovascular Diseases : NMCD. Jul, 2022 | Pubmed ID: 35527126 C-reactive Protein in Adult Samoans: Population Variation and Physiological Correlates American Journal of Human Biology : the Official Journal of the Human Biology Council. Mar, 2022 | Pubmed ID: 34260111 Pharmacological Inhibition of Adipose Tissue Adipose Triglyceride Lipase by Atglistatin Prevents Catecholamine-induced Myocardial Damage Cardiovascular Research. Aug, 2022 | Pubmed ID: 34061169 Mechanistic Studies of PEG-asparaginase-induced Liver Injury and Hepatic Steatosis in Mice Acta Pharmaceutica Sinica. B. Dec, 2021 | Pubmed ID: 35024306 A Murine Model of the Human CREBRFR457Q Obesity-risk Variant Does Not Influence Energy or Glucose Homeostasis in Response to Nutritional Stress PloS One. 2021 | Pubmed ID: 34520472 Body Size and Composition of Samoan Toddlers Aged 18-25 Months in 2019 Annals of Human Biology. Jun, 2021 | Pubmed ID: 34340601 Quantifying the Progression of Non-alcoholic Fatty Liver Disease in Human Biomimetic Liver Microphysiology Systems with Fluorescent Protein Biosensors Experimental Biology and Medicine (Maywood, N.J.). Nov, 2021 | Pubmed ID: 33957803 Advanced Lipodystrophy Reverses Fatty Liver in Mice Lacking Adipocyte Hormone-sensitive Lipase Communications Biology. Mar, 2021 | Pubmed ID: 33692445 Inhibition of ATGL in Adipose Tissue Ameliorates Isoproterenol-induced Cardiac Remodeling by Reducing Adipose Tissue Inflammation American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2021 | Pubmed ID: 33185110 Exploring the Paradoxical Relationship of a Creb 3 Regulatory Factor Missense Variant With Body Mass Index and Diabetes Among Samoans: Protocol for the Soifua Manuia (Good Health) Observational Cohort Study JMIR Research Protocols. Jul, 2020 | Pubmed ID: 32706746 Pancreatic Triglyceride Lipase Mediates Lipotoxic Systemic Inflammation The Journal of Clinical Investigation. Apr, 2020 | Pubmed ID: 31917686 Decreased Mitochondrial Dynamics Is Associated with Insulin Resistance, Metabolic Rate, and Fitness in African Americans The Journal of Clinical Endocrinology and Metabolism. Apr, 2020 | Pubmed ID: 31833547 Symptoms and Dietary Impact in Hypertriglyceridemia-Associated Pancreatitis: Development and Content Validity of Two New Measures PharmacoEconomics - Open. Mar, 2020 | Pubmed ID: 31250380 The ZJU Index is a Powerful Surrogate Marker for NAFLD in Severely Obese North American Women PloS One. 2019 | Pubmed ID: 31770380 Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality Nutrients. Oct, 2019 | Pubmed ID: 31652734 Impact of Hepatic Steatosis on Resting Metabolic Rate and Metabolic Adaptation in Response to Intentional Weight Loss Hepatology Communications. Oct, 2019 | Pubmed ID: 31592493 Wnt Pathway Inhibitor DKK1: A Potential Novel Biomarker for Adiposity Journal of the Endocrine Society. Feb, 2019 | Pubmed ID: 30746507 Adipose Tissue-derived Free Fatty Acids Initiate Myeloid Cell Accumulation in Mouse Liver in States of Lipid Oversupply American Journal of Physiology. Endocrinology and Metabolism. Nov, 2018 | Pubmed ID: 30086648 Atglistatin Ameliorates Functional Decline in Heart Failure Via Adipocyte-specific Inhibition of Adipose Triglyceride Lipase American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2018 | Pubmed ID: 29932770 Jak-TGFβ Cross-talk Links Transient Adipose Tissue Inflammation to Beige Adipogenesis Science Signaling. Apr, 2018 | Pubmed ID: 29692363 Brown Adipose Tissue Whitening Leads to Brown Adipocyte Death and Adipose Tissue Inflammation Journal of Lipid Research. May, 2018 | Pubmed ID: 29599420 Adipose Tissue ATGL Modifies the Cardiac Lipidome in Pressure-overload-induced Left Ventricular Failure PLoS Genetics. Jan, 2018 | Pubmed ID: 29320510 Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue Cell Metabolism. Nov, 2017 | Pubmed ID: 28988821 Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines As a Fuel Source for Brown Fat Thermogenesis Cell Metabolism. Sep, 2017 | Pubmed ID: 28877455 Single-Step QPCR and DPCR Detection of Diverse CRISPR-Cas9 Gene Editing Events G3 (Bethesda, Md.). Oct, 2017 | Pubmed ID: 28860183 Fatty Acid Oxidation by the Osteoblast is Required for Normal Bone Acquisition in a Sex- and Diet-dependent Manner JCI Insight. Aug, 2017 | Pubmed ID: 28814665 Differential Impact of Weight Loss on Nonalcoholic Fatty Liver Resolution in a North American Cohort with Obesity Obesity (Silver Spring, Md.). Aug, 2017 | Pubmed ID: 28605159 Kidney Triglyceride Accumulation in the Fasted Mouse is Dependent Upon Serum Free Fatty Acids Journal of Lipid Research. Jun, 2017 | Pubmed ID: 28404638 Autotaxin Is Regulated by Glucose and Insulin in Adipocytes Endocrinology. Apr, 2017 | Pubmed ID: 28324037 Liver X Receptor Mediates Hepatic Triglyceride Accumulation Through Upregulation of G0/G1 Switch Gene 2 Expression JCI Insight. Feb, 2017 | Pubmed ID: 28239648 A Thrifty Variant in CREBRF Strongly Influences Body Mass Index in Samoans Nature Genetics. Sep, 2016 | Pubmed ID: 27455349 Abnormal Lipid Processing but Normal Long-term Repopulation Potential of Myc-/- Hepatocytes Oncotarget. May, 2016 | Pubmed ID: 27105497 Serum Autotaxin/ENPP2 Correlates with Insulin Resistance in Older Humans with Obesity Obesity (Silver Spring, Md.). Dec, 2015 | Pubmed ID: 26727116 Three-Dimensional Adipocyte Culture: The Next Frontier for Adipocyte Biology Discovery Endocrinology. Dec, 2015 | Pubmed ID: 26492473 Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity PloS One. 2015 | Pubmed ID: 26397111 Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate The Journal of Biological Chemistry. Sep, 2015 | Pubmed ID: 26260790 Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice Endocrinology. Oct, 2015 | Pubmed ID: 26196542 Adipose Triglyceride Lipase Acts on Neutrophil Lipid Droplets to Regulate Substrate Availability for Lipid Mediator Synthesis Journal of Leukocyte Biology. Nov, 2015 | Pubmed ID: 26109679 Serum Autotaxin is Independently Associated with Hepatic Steatosis in Women with Severe Obesity Obesity (Silver Spring, Md.). May, 2015 | Pubmed ID: 25865747 Adipose Triglyceride Lipase Deletion from Adipocytes, but Not Skeletal Myocytes, Impairs Acute Exercise Performance in Mice American Journal of Physiology. Endocrinology and Metabolism. May, 2015 | Pubmed ID: 25783895 Fasting-induced G0/G1 Switch Gene 2 and FGF21 Expression in the Liver Are Under Regulation of Adipose Tissue Derived Fatty Acids Journal of Hepatology. Aug, 2015 | Pubmed ID: 25733154 Coupling of Lipolysis and De Novo Lipogenesis in Brown, Beige, and White Adipose Tissues During Chronic β3-adrenergic Receptor Activation Journal of Lipid Research. Nov, 2014 | Pubmed ID: 25193997 Skeletal Muscle Triacylglycerol Hydrolysis Does Not Influence Metabolic Complications of Obesity Diabetes. Oct, 2013 | Pubmed ID: 23835334 Adipose Triglyceride Lipase is a TG Hydrolase of the Small Intestine and Regulates Intestinal PPARα Signaling Journal of Lipid Research. Feb, 2013 | Pubmed ID: 23220585 Regulation of Insulin and Leptin Signaling by Muscle Suppressor of Cytokine Signaling 3 (SOCS3) PloS One. 2012 | Pubmed ID: 23115649 Adiponutrin Functions As a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase Cell Metabolism. May, 2012 | Pubmed ID: 22560221 ATGL-mediated Fat Catabolism Regulates Cardiac Mitochondrial Function Via PPAR-α and PGC-1 Nature Medicine. Aug, 2011 | Pubmed ID: 21857651 Transcriptional Control of Adipose Lipid Handling by IRF4 Cell Metabolism. Mar, 2011 | Pubmed ID: 21356515 Pnpla3/Adiponutrin Deficiency in Mice Does Not Contribute to Fatty Liver Disease or Metabolic Syndrome Journal of Lipid Research. Feb, 2011 | Pubmed ID: 21068004 Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19723629 Early Structural and Metabolic Cardiac Remodelling in Response to Inducible Adipose Triglyceride Lipase Ablation Cardiovascular Research. | Pubmed ID: 23708736 Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice from the Development of Lipotoxic Cardiomyopathy Diabetes. | Pubmed ID: 23349479 Myocardial ATGL Overexpression Decreases the Reliance on Fatty Acid Oxidation and Protects Against Pressure Overload-induced Cardiac Dysfunction Molecular and Cellular Biology. | Pubmed ID: 22158969 Author Spotlight: Deciphering the Cellular Mysteries of Intermuscular Adipose Tissue in Humans Line O. Elingaard-Larsen1,2, Katie L. Whytock1, Adeline Divoux1, Meghan Hopf1, Erin E. Kershaw3, Jamie N. Justice4, Bret H. Goodpaster1, Nancy E. Lane5, Lauren M. Sparks1 1Translational Research Institute, AdventHealth, 2Steno Diabetes Center Copenhagen, 3Division of Endocrinology and Metabolism, University of Pittsburgh, 4Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, 5Department of Internal Medicine - Rheumatology, Allergy, and Clinical Immunology, University of California Davis Health JoVE 66784 생물학
Author Spotlight: Deciphering the Cellular Mysteries of Intermuscular Adipose Tissue in Humans Line O. Elingaard-Larsen1,2, Katie L. Whytock1, Adeline Divoux1, Meghan Hopf1, Erin E. Kershaw3, Jamie N. Justice4, Bret H. Goodpaster1, Nancy E. Lane5, Lauren M. Sparks1 1Translational Research Institute, AdventHealth, 2Steno Diabetes Center Copenhagen, 3Division of Endocrinology and Metabolism, University of Pittsburgh, 4Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, 5Department of Internal Medicine - Rheumatology, Allergy, and Clinical Immunology, University of California Davis Health JoVE 66784 생물학