Marcela Brissova Biography Publications JoVE Articles Marcela Brissova has not added a biography. If you are Marcela Brissova and would like to personalize this page please email our Author Liaison for assistance. Publications Exocrine Pancreas in Type 1 and Type 2 Diabetes: Different Patterns of Fibrosis, Metaplasia, Angiopathy, and Adiposity Diabetes. Oct, 2023 | Pubmed ID: 37881846 The Human α Cell in Health and Disease The Journal of Endocrinology. Jul, 2023 | Pubmed ID: 37114672 Human Pancreatic Capillaries and Nerve Fibers Persist in Type 1 Diabetes Despite Beta Cell Loss American Journal of Physiology. Endocrinology and Metabolism. Mar, 2023 | Pubmed ID: 36696598 Images From the Exeter Archival Diabetes Biobank Now Accessible Via Pancreatlas Diabetes Care. Dec, 2022 | Pubmed ID: 36239401 Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes Journal of the Endocrine Society. Dec, 2021 | Pubmed ID: 34870058 Microvessels Enhance Vascularization and Function of Transplanted Insulin-producing Cells Cell Metabolism. Nov, 2021 | Pubmed ID: 34731653 Combinatorial Transcription Factor Profiles Predict Mature and Functional Human Islet α and β Cells JCI Insight. Sep, 2021 | Pubmed ID: 34428183 The Human Islet: Mini-Organ With Mega-Impact Endocrine Reviews. Sep, 2021 | Pubmed ID: 33844836 Coordinated Interactions Between Endothelial Cells and Macrophages in the Islet Microenvironment Promote β Cell Regeneration NPJ Regenerative Medicine. Apr, 2021 | Pubmed ID: 33824346 Dopamine Regulates Pancreatic Glucagon and Insulin Secretion Via Adrenergic and Dopaminergic Receptors Translational Psychiatry. Feb, 2021 | Pubmed ID: 33589583 Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease Patterns (New York, N.Y.). Nov, 2020 | Pubmed ID: 33294866 SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells Cell Metabolism. Dec, 2020 | Pubmed ID: 33207245 Decreased Pancreatic Acinar Cell Number in Type 1 Diabetes Diabetologia. Jul, 2020 | Pubmed ID: 32388592 Integrated Human Pseudoislet System and Microfluidic Platform Demonstrate Differences in GPCR Signaling in Islet Cells JCI Insight. May, 2020 | Pubmed ID: 32352931 Modeling Monogenic Diabetes Using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A Cell Stem Cell. Aug, 2019 | Pubmed ID: 31374199 The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles Diabetes. Jul, 2019 | Pubmed ID: 31092479 The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles Diabetologia. Jul, 2019 | Pubmed ID: 31089753 Imaging Mass Spectrometry Enables Molecular Profiling of Mouse and Human Pancreatic Tissue Diabetologia. Jun, 2019 | Pubmed ID: 30955045 HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes Diabetes. May, 2019 | Pubmed ID: 30833470 Human Islets Expressing HNF1A Variant Have Defective β Cell Transcriptional Regulatory Networks The Journal of Clinical Investigation. Jan, 2019 | Pubmed ID: 30507613 Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis Cell Metabolism. Mar, 2019 | Pubmed ID: 30449685 Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally Diabetes. Feb, 2019 | Pubmed ID: 30425060 β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes Diabetes. Nov, 2018 | Pubmed ID: 30150306 Cystic Fibrosis-related Diabetes is Caused by Islet Loss and Inflammation JCI Insight. Apr, 2018 | Pubmed ID: 29669939 α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes Cell Reports. Mar, 2018 | Pubmed ID: 29514095 Mouse Pancreatic Islet Macrophages Use Locally Released ATP to Monitor Beta Cell Activity Diabetologia. Jan, 2018 | Pubmed ID: 28884198 Glycoprotein 2 is a Specific Cell Surface Marker of Human Pancreatic Progenitors Nature Communications. Aug, 2017 | Pubmed ID: 28835709 Analysis of Self-antigen Specificity of Islet-infiltrating T Cells from Human Donors with Type 1 Diabetes Nature Medicine. Dec, 2016 | Pubmed ID: 27798614 Development of a Reliable Automated Screening System to Identify Small Molecules and Biologics That Promote Human β-cell Regeneration American Journal of Physiology. Endocrinology and Metabolism. Nov, 2016 | Pubmed ID: 27624103 Inactivating the Permanent Neonatal Diabetes Gene Mnx1 Switches Insulin-producing β-cells to a δ-like Fate and Reveals a Facultative Proliferative Capacity in Aged β-cells Development (Cambridge, England). Nov, 2015 | Pubmed ID: 26534984 Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells Developmental Cell. Sep, 2015 | Pubmed ID: 26418295 Human Islets Have Fewer Blood Vessels Than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 08, 2015 | Pubmed ID: 26216139 Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25851902 Human Islet Preparations Distributed for Research Exhibit a Variety of Insulin-secretory Profiles American Journal of Physiology. Endocrinology and Metabolism. Apr, 2015 | Pubmed ID: 25648831 Automated Quantification of Pancreatic β-cell Mass American Journal of Physiology. Endocrinology and Metabolism. Jun, 2014 | Pubmed ID: 24760991 Pancreas Development in Humans Current Opinion in Endocrinology, Diabetes, and Obesity. Apr, 2014 | Pubmed ID: 24569548 Islet Microenvironment, Modulated by Vascular Endothelial Growth Factor-A Signaling, Promotes β Cell Regeneration Cell Metabolism. Mar, 2014 | Pubmed ID: 24561261 Vascular Endothelial Growth Factor-a and Islet Vascularization Are Necessary in Developing, but Not Adult, Pancreatic Islets Diabetes. Dec, 2013 | Pubmed ID: 23884891 Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis Diabetes. Dec, 2013 | Pubmed ID: 23630302 Enhanced Expression of VEGF-A in β Cells Increases Endothelial Cell Number but Impairs Islet Morphogenesis and β Cell Proliferation Developmental Biology. Jul, 2012 | Pubmed ID: 22546694 Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 Expression Using Targeted Contrast-enhanced High-frequency Ultrasonography Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Nov, 2007 | Pubmed ID: 17957052 Ponteggi Polimero Come Microambienti Sintetici Per Trapianto Isolotto Extraepatica Transplantation. Aug, 2006 | Pubmed ID: 16926587 H-Ras, R-Ras, and TC21 Differentially Regulate Ureteric Bud Cell Branching Morphogenesis Molecular Biology of the Cell. Apr, 2006 | Pubmed ID: 16467383 Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets Diabetes. May, 2004 | Pubmed ID: 15111502 A Fall in Portal Vein Insulin Does Not Cause the Alpha-cell Response to Mild, Non-insulin-induced Hypoglycemia in Conscious Dogs Metabolism: Clinical and Experimental. Nov, 2003 | Pubmed ID: 14624400 Assessment of Insulin Secretion in the Mouse Methods in Molecular Medicine. 2003 | Pubmed ID: 12619713