Stephen R. Farmer Department of Biochemistry Boston University School of Medicine Biography Publications Institution JoVE Articles Stephen R. Farmer has not added a biography. If you are Stephen R. Farmer and would like to personalize this page please email our Author Liaison for assistance. Publications Shifts of Immune Cell Populations Differ in Response to Different Effectors of Beige Remodeling of Adipose Tissue IScience. Dec, 2020 | Pubmed ID: 33294778 The Adipocyte Acquires a Fibroblast-Like Transcriptional Signature in Response to a High Fat Diet Scientific Reports. 02, 2020 | Pubmed ID: 32047213 CIDEA Transcriptionally Regulates UCP1 for Britening and Thermogenesis in Human Fat Cells IScience. Oct, 2019 | Pubmed ID: 31563853 Adipose Progenitor Cells Contribute to Lipid Spillover During Obesity Trends in Endocrinology and Metabolism: TEM. 07, 2019 | Pubmed ID: 31153731 Boning Up on Irisin The New England Journal of Medicine. 04, 2019 | Pubmed ID: 30970196 Toll-Like Receptor-4 Disruption Suppresses Adipose Tissue Remodeling and Increases Survival in Cancer Cachexia Syndrome Scientific Reports. 12, 2018 | Pubmed ID: 30575787 Aortic Carboxypeptidase-like Protein Enhances Adipose Tissue Stromal Progenitor Differentiation into Myofibroblasts and is Upregulated in Fibrotic White Adipose Tissue PloS One. 2018 | Pubmed ID: 29799877 Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors During Obesity-Induced Adipose Tissue Fibrosis Cell Reports. 05, 2018 | Pubmed ID: 29768198 CDK6 Inhibits White to Beige Fat Transition by Suppressing RUNX1 Nature Communications. 03, 2018 | Pubmed ID: 29523786 Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1 Adipocytes Cell Metabolism. 12, 2016 | Pubmed ID: 27974179 Myocardin-related Transcription Factor A (MRTFA) Regulates the Fate of Bone Marrow Mesenchymal Stem Cells and Its Absence in Mice Leads to Osteopenia Molecular Metabolism. Oct, 2016 | Pubmed ID: 27689009 LSD1-a Pivotal Epigenetic Regulator of Brown and Beige Fat Differentiation and Homeostasis Genes & Development. 08, 2016 | Pubmed ID: 27601528 Morphogenetics in Brown, Beige and White Fat Development Adipocyte. Apr-Jun, 2016 | Pubmed ID: 27386157 Myocardin-related Transcription Factor A Regulates Conversion of Progenitors to Beige Adipocytes Cell. Jan, 2015 | Pubmed ID: 25579684 Ablation of TRIP-Br2, a Regulator of Fat Lipolysis, Thermogenesis and Oxidative Metabolism, Prevents Diet-induced Obesity and Insulin Resistance Nature Medicine. Feb, 2013 | Pubmed ID: 23291629 Brown Remodeling of White Adipose Tissue by SirT1-dependent Deacetylation of Pparγ Cell. Aug, 2012 | Pubmed ID: 22863012 Recruitment of Brown Adipose Tissue As a Therapy for Obesity-associated Diseases Frontiers in Endocrinology. 2012 | Pubmed ID: 22654854 Roles for Peroxisome Proliferator-activated Receptor γ (PPARγ) and PPARγ Coactivators 1α and 1β in Regulating Response of White and Brown Adipocytes to Hypoxia The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22493496 The Multi-level Action of Fatty Acids on Adiponectin Production by Fat Cells PloS One. 2011 | Pubmed ID: 22140527 SIRT1 Controls Lipolysis in Adipocytes Via FOXO1-mediated Expression of ATGL Journal of Lipid Research. Sep, 2011 | Pubmed ID: 21743036 Brown Adipose Tissue: a Promising Target to Combat Obesity Drug News & Perspectives. Sep, 2010 | Pubmed ID: 20862392 Mechanisms Regulating Repression of Haptoglobin Production by Peroxisome Proliferator-activated Receptor-gamma Ligands in Adipocytes Endocrinology. Feb, 2010 | Pubmed ID: 19952271 Mechanisms of Obesity and Related Pathologies: Transcriptional Control of Adipose Tissue Development The FEBS Journal. Oct, 2009 | Pubmed ID: 19754874 C/EBPalpha and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes During Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-activated Receptor Gamma Agonists Molecular and Cellular Biology. Sep, 2009 | Pubmed ID: 19564408 Brown Fat and Skeletal Muscle: Unlikely Cousins? Cell. Sep, 2008 | Pubmed ID: 18775306 Molecular Determinants of Brown Adipocyte Formation and Function Genes & Development. May, 2008 | Pubmed ID: 18483216 Identification of a Domain Within Peroxisome Proliferator-activated Receptor Gamma Regulating Expression of a Group of Genes Containing Fibroblast Growth Factor 21 That Are Selectively Repressed by SIRT1 in Adipocytes Molecular and Cellular Biology. Jan, 2008 | Pubmed ID: 17954559 Cell Differentiation Current Opinion in Cell Biology. Dec, 2007 | Pubmed ID: 19050740 TRB3 Blocks Adipocyte Differentiation Through the Inhibition of C/EBPbeta Transcriptional Activity Molecular and Cellular Biology. Oct, 2007 | Pubmed ID: 17646392 Peroxisome Proliferator-activated Receptor Gamma Interacts with CIITA X RFX5 Complex to Repress Type I Collagen Gene Expression The Journal of Biological Chemistry. Sep, 2007 | Pubmed ID: 17611194 Adiponectin Secretion is Regulated by SIRT1 and the Endoplasmic Reticulum Oxidoreductase Ero1-L Alpha Molecular and Cellular Biology. Jul, 2007 | Pubmed ID: 17452443 Transcriptional Control of Adipocyte Formation Cell Metabolism. Oct, 2006 | Pubmed ID: 17011499 Functional Interaction Between Peroxisome Proliferator-activated Receptor Gamma and Beta-catenin Molecular and Cellular Biology. Aug, 2006 | Pubmed ID: 16847334 Thiazolidinediones Can Rapidly Activate AMP-activated Protein Kinase in Mammalian Tissues American Journal of Physiology. Endocrinology and Metabolism. Jul, 2006 | Pubmed ID: 16464908 Activation of CCAAT/enhancer-binding Protein (C/EBP) Alpha Expression by C/EBP Beta During Adipogenesis Requires a Peroxisome Proliferator-activated Receptor-gamma-associated Repression of HDAC1 at the C/ebp Alpha Gene Promoter The Journal of Biological Chemistry. Mar, 2006 | Pubmed ID: 16431920 C/EBPalpha-dependent Induction of Glutathione S-transferase Zeta/maleylacetoacetate Isomerase (GSTzeta/MAAI) Expression During the Differentiation of Mouse Fibroblasts into Adipocytes Biochemical and Biophysical Research Communications. Feb, 2006 | Pubmed ID: 16376852 Phosphorylation of C/EBPbeta at a Consensus Extracellular Signal-regulated Kinase/glycogen Synthase Kinase 3 Site is Required for the Induction of Adiponectin Gene Expression During the Differentiation of Mouse Fibroblasts into Adipocytes Molecular and Cellular Biology. Oct, 2004 | Pubmed ID: 15367685 Regulating the Balance Between Peroxisome Proliferator-activated Receptor Gamma and Beta-catenin Signaling During Adipogenesis. A Glycogen Synthase Kinase 3beta Phosphorylation-defective Mutant of Beta-catenin Inhibits Expression of a Subset of Adipogenic Genes The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15308623 Glut4 Storage Vesicles Without Glut4: Transcriptional Regulation of Insulin-dependent Vesicular Traffic Molecular and Cellular Biology. Aug, 2004 | Pubmed ID: 15282314 The Forkhead Transcription Factor FoxC2 Inhibits White Adipocyte Differentiation The Journal of Biological Chemistry. Oct, 2004 | Pubmed ID: 15277530 Peroxisome-proliferator-activated Receptor Gamma Suppresses Wnt/beta-catenin Signalling During Adipogenesis The Biochemical Journal. Dec, 2003 | Pubmed ID: 12954078 The Forkhead Transcription Factor Foxo1: a Possible Link Between Obesity and Insulin Resistance Molecular Cell. Jan, 2003 | Pubmed ID: 12535515 Activation of MEK/ERK Signaling Promotes Adipogenesis by Enhancing Peroxisome Proliferator-activated Receptor Gamma (PPARgamma ) and C/EBPalpha Gene Expression During the Differentiation of 3T3-L1 Preadipocytes The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12270934 Octanoate Attenuates Adipogenesis in 3T3-L1 Preadipocytes The Journal of Nutrition. May, 2002 | Pubmed ID: 11983812 Three-Dimensional Adipocyte Culture as a Model to Study Cachexia-Induced White Adipose Tissue Remodeling Miguel L Batista Jr.1,2, Tova Meshulam2,3, Kathleen Desevin2, Nabil Rabhi2, Stephen R. Farmer2 1Department of Integrated Biotechnology, University of Mogi das Cruzes, 2Department of Biochemistry, Boston University School of Medicine, 3Obesity Research Center, Department of Medicine, Boston University School of Medicine JoVE 61853 생물학
Three-Dimensional Adipocyte Culture as a Model to Study Cachexia-Induced White Adipose Tissue Remodeling Miguel L Batista Jr.1,2, Tova Meshulam2,3, Kathleen Desevin2, Nabil Rabhi2, Stephen R. Farmer2 1Department of Integrated Biotechnology, University of Mogi das Cruzes, 2Department of Biochemistry, Boston University School of Medicine, 3Obesity Research Center, Department of Medicine, Boston University School of Medicine JoVE 61853 생물학