Stuart J. Forbes Scottish Centre for Regenerative Medicine University of Edinburgh Biography Publications Institution JoVE Articles Stuart J. Forbes has not added a biography. If you are Stuart J. Forbes and would like to personalize this page please email our Author Liaison for assistance. Publications TFEB Regulates Murine Liver Cell Fate During Development and Regeneration Nature Communications. May, 2020 | Pubmed ID: 32424153 Absolute Measurement of the Tissue Origins of Cell-free DNA in the Healthy State and Following Paracetamol Overdose BMC Medical Genomics. Apr, 2020 | Pubmed ID: 32252771 Regional Differences in Human Biliary Tissues and Corresponding in Vitro Derived Organoids Hepatology (Baltimore, Md.). Mar, 2020 | Pubmed ID: 32222998 Expansion, in Vivo-ex Vivo Cycling, and Genetic Manipulation of Primary Human Hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31915293 Peribiliary Gland Niche Participates in Biliary Tree Regeneration in Mouse and in Human Primary Sclerosing Cholangitis Hepatology (Baltimore, Md.). Mar, 2020 | Pubmed ID: 31330051 Modulation of Biliary Cancer Chemo-resistance Through MicroRNA-mediated Rewiring of the Expansion of CD133+ Cells Hepatology (Baltimore, Md.). Dec, 2019 | Pubmed ID: 31879968 Epigenetic Remodelling Licences Adult Cholangiocytes for Organoid Formation and Liver Regeneration Nature Cell Biology. 11, 2019 | Pubmed ID: 31685987 Safety Profile of Autologous Macrophage Therapy for Liver Cirrhosis Nature Medicine. 10, 2019 | Pubmed ID: 31591593 Macrophages As a Cell-Based Therapy for Liver Disease Seminars in Liver Disease. 11, 2019 | Pubmed ID: 31242527 Beneficial Noncancerous Mutations in Liver Disease Trends in Genetics : TIG. 07, 2019 | Pubmed ID: 31151757 Quantifying Changes in Innate Immune Function Following Liver Transplantation for Chronic Liver Disease HPB : the Official Journal of the International Hepato Pancreato Biliary Association. 10, 2019 | Pubmed ID: 30850189 An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade Cancer Research. 04, 2019 | Pubmed ID: 30674531 Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice Stem Cells Translational Medicine. 03, 2019 | Pubmed ID: 30394698 Cellular Plasticity in Liver Regeneration: Spotlight on Cholangiocytes Hepatology (Baltimore, Md.). May, 2019 | Pubmed ID: 30382597 Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes Hepatology (Baltimore, Md.). 02, 2019 | Pubmed ID: 30215850 Telomerase Activity Links to Regenerative Capacity of Hepatocytes Transplantation. 10, 2018 | Pubmed ID: 30247437 3D Human Liver Tissue from Pluripotent Stem Cells Displays Stable Phenotype in Vitro and Supports Compromised Liver Function in Vivo Archives of Toxicology. 10, 2018 | Pubmed ID: 30155720 TGFβ Inhibition Restores a Regenerative Response in Acute Liver Injury by Suppressing Paracrine Senescence Science Translational Medicine. 08, 2018 | Pubmed ID: 30111642 Paracrine Cellular Senescence Exacerbates Biliary Injury and Impairs Regeneration Nature Communications. 03, 2018 | Pubmed ID: 29523787 Studies of Macrophage Therapy for Cirrhosis - From Mice to Men Journal of Hepatology. 05, 2018 | Pubmed ID: 29317297 GADD45β Loss Ablates Innate Immunosuppression in Cancer Cancer Research. 03, 2018 | Pubmed ID: 29279355 The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury Journal of Immunology (Baltimore, Md. : 1950). 02, 2018 | Pubmed ID: 29263216 11Beta-hydroxysteroid Dehydrogenase-1 Deficiency or Inhibition Enhances Hepatic Myofibroblast Activation in Murine Liver Fibrosis Hepatology (Baltimore, Md.). 06, 2018 | Pubmed ID: 29251794 Raman Spectroscopy and Regenerative Medicine: a Review NPJ Regenerative Medicine. 2017 | Pubmed ID: 29302348 Cholangiocytes Act As Facultative Liver Stem Cells During Impaired Hepatocyte Regeneration Nature. 07, 2017 | Pubmed ID: 28700576 Development, Functional Characterization and Validation of Methodology for GMP-compliant Manufacture of Phagocytic Macrophages: A Novel Cellular Therapeutic for Liver Cirrhosis Cytotherapy. 09, 2017 | Pubmed ID: 28673774 Milk Fat Globule-EGF Factor 8 for Liver Fibrosis Therapy: Creaming Off the Beneficial Effects of Mesenchymal Stromal Cells Gastroenterology. 04, 2017 | Pubmed ID: 28259796 Functionalized Superparamagnetic Iron Oxide Nanoparticles Provide Highly Efficient Iron-labeling in Macrophages for Magnetic Resonance-based Detection in Vivo Cytotherapy. 04, 2017 | Pubmed ID: 28214127 Wnt Signalling Modulates Transcribed-ultraconserved Regions in Hepatobiliary Cancers Gut. 07, 2017 | Pubmed ID: 27618837 Advances in Cholangiocarcinoma Research: Report from the Third Cholangiocarcinoma Foundation Annual Conference Journal of Gastrointestinal Oncology. Dec, 2016 | Pubmed ID: 28078106 Notch3 Drives Development and Progression of Cholangiocarcinoma Proceedings of the National Academy of Sciences of the United States of America. 10, 2016 | Pubmed ID: 27791012 Interleukin-13 Activates Distinct Cellular Pathways Leading to Ductular Reaction, Steatosis, and Fibrosis Immunity. 07, 2016 | Pubmed ID: 27421703 Liver Regeneration - Mechanisms and Models to Clinical Application Nature Reviews. Gastroenterology & Hepatology. 08, 2016 | Pubmed ID: 27353402 Corrigendum to "Alternatively Activated (M2) Macrophages Promote Tumour Growth and Invasiveness in Hepatocellular Carcinoma" [J Hepatol 2015;62:607-616] Journal of Hepatology. Jun, 2016 | Pubmed ID: 27198050 Expert Consensus Document: Cholangiocarcinoma: Current Knowledge and Future Perspectives Consensus Statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) Nature Reviews. Gastroenterology & Hepatology. 05, 2016 | Pubmed ID: 27095655 The RSPO-LGR4/5-ZNRF3/RNF43 Module Controls Liver Zonation and Size Nature Cell Biology. 05, 2016 | Pubmed ID: 27088858 Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs Stem Cells Translational Medicine. Jun, 2016 | Pubmed ID: 27057006 Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells Journal of the American Society of Nephrology : JASN. Nov, 2016 | Pubmed ID: 27020854 Recombinant Laminins Drive the Differentiation and Self-Organization of HESC-Derived Hepatocytes Stem Cell Reports. Dec, 2015 | Pubmed ID: 26626180 Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells Following Expansion in Long Term Adherent Culture PloS One. 2015 | Pubmed ID: 26457418 Two Fresh Streams to Fill the Liver's Hepatocyte Pool Cell Stem Cell. Oct, 2015 | Pubmed ID: 26431179 CSF1 Restores Innate Immunity After Liver Injury in Mice And Serum Levels Indicate Outcomes of Patients With Acute Liver Failure Gastroenterology. Dec, 2015 | Pubmed ID: 26344055 Phenotypic and Functional Characterization of Macrophages with Therapeutic Potential Generated from Human Cirrhotic Monocytes in a Cohort Study Cytotherapy. Nov, 2015 | Pubmed ID: 26342993 Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015) Advanced Healthcare Materials. Aug, 2015 | Pubmed ID: 26308957 Hepatic Progenitor Cells of Biliary Origin with Liver Repopulation Capacity Nature Cell Biology. Aug, 2015 | Pubmed ID: 26192438 Organoid Cultures Boost Human Liver Cell Expansion Hepatology (Baltimore, Md.). Nov, 2015 | Pubmed ID: 26146934 Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance Advanced Healthcare Materials. Aug, 2015 | Pubmed ID: 26109270 Alternatively Activated (M2) Macrophages Promote Tumour Growth and Invasiveness in Hepatocellular Carcinoma Journal of Hepatology. Mar, 2015 | Pubmed ID: 25450711 Preparing the Ground for Tissue Regeneration: from Mechanism to Therapy Nature Medicine. Aug, 2014 | Pubmed ID: 25100531 Galectin-3 Regulates Hepatic Progenitor Cell Expansion During Liver Injury Gut. May, 2014 | Pubmed ID: 24837171 Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome Case Reports in Transplantation. 2014 | Pubmed ID: 24600525 Polysialic Acid/neural Cell Adhesion Molecule Modulates the Formation of Ductular Reactions in Liver Injury Hepatology (Baltimore, Md.). Nov, 2014 | Pubmed ID: 24585441 Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: a Role for Bone Marrow Derived Macrophages PloS One. 2014 | Pubmed ID: 24475094 CD133+ Cancer Stem-like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant but Sensitive to a Novel Neuropeptide Antagonist Cancer Research. Mar, 2014 | Pubmed ID: 24436149 Links Between Hepatic Fibrosis, Ductular Reaction, and Progenitor Cell Expansion Gastroenterology. Feb, 2014 | Pubmed ID: 24315991 Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma Cancer Research. Feb, 2014 | Pubmed ID: 24310400 Relaxin Modulates Human and Rat Hepatic Myofibroblast Function and Ameliorates Portal Hypertension in Vivo Hepatology (Baltimore, Md.). Apr, 2014 | Pubmed ID: 23873655 Differentiation of Progenitors in the Liver: a Matter of Local Choice The Journal of Clinical Investigation. May, 2013 | Pubmed ID: 23635784 Suppression of Epithelial to Mesenchymal Transitioning (EMT) Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Towards Functional Insulin Producing β-Like Cells Diabetes. Apr, 2013 | Pubmed ID: 23610058 Bone Marrow Injection Stimulates Hepatic Ductular Reactions in the Absence of Injury Via Macrophage-mediated TWEAK Signaling Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23576749 Liver Sinusoidal Endothelial Cells in Disease--and for Therapy? Journal of Hepatology. Jan, 2013 | Pubmed ID: 22892397 Differential Ly-6C Expression Identifies the Recruited Macrophage Phenotype, Which Orchestrates the Regression of Murine Liver Fibrosis Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23100531 Macrophage-derived Wnt Opposes Notch Signaling to Specify Hepatic Progenitor Cell Fate in Chronic Liver Disease Nature Medicine. Apr, 2012 | Pubmed ID: 22388089 Elastin Accumulation is Regulated at the Level of Degradation by Macrophage Metalloelastase (MMP-12) During Experimental Liver Fibrosis Hepatology (Baltimore, Md.). Jun, 2012 | Pubmed ID: 22223197 Regulation of Transforming Growth Factor-β1-driven Lung Fibrosis by Galectin-3 American Journal of Respiratory and Critical Care Medicine. Mar, 2012 | Pubmed ID: 22095546 Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis American Journal of Respiratory and Critical Care Medicine. Sep, 2011 | Pubmed ID: 21680953 Liver Fibrogenic Cells Best Practice & Research. Clinical Gastroenterology. Apr, 2011 | Pubmed ID: 21497739 Matrix Stiffness Modulates Proliferation, Chemotherapeutic Response, and Dormancy in Hepatocellular Carcinoma Cells Hepatology (Baltimore, Md.). Apr, 2011 | Pubmed ID: 21442631 Macrophage Therapy for Murine Liver Fibrosis Recruits Host Effector Cells Improving Fibrosis, Regeneration, and Function Hepatology (Baltimore, Md.). Jun, 2011 | Pubmed ID: 21433043 Unbiased Screening of Polymer Libraries to Define Novel Substrates for Functional Hepatocytes with Inducible Drug Metabolism Stem Cell Research. Mar, 2011 | Pubmed ID: 21277274 Persistence of Functional Hepatocyte-like Cells in Immune-compromised Mice Liver International : Official Journal of the International Association for the Study of the Liver. Feb, 2011 | Pubmed ID: 21143581 Prospects for Stem Cell Transplantation in the Treatment of Hepatic Disease Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jul, 2010 | Pubmed ID: 20583084 Characterisation of a Stereotypical Cellular and Extracellular Adult Liver Progenitor Cell Niche in Rodents and Diseased Human Liver Gut. May, 2010 | Pubmed ID: 20427399 Portal Venous Endothelium in Developing Human Liver Contains Haematopoietic and Epithelial Progenitor Cells Experimental Cell Research. May, 2010 | Pubmed ID: 20211168 Liver Development, Regeneration, and Carcinogenesis Journal of Biomedicine & Biotechnology. 2010 | Pubmed ID: 20169172 Practical Barriers to Delivering Autologous Bone Marrow Stem Cell Therapy As an Adjunct to Liver Resection Stem Cells and Development. Feb, 2010 | Pubmed ID: 19954303 Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells Hepatology (Baltimore, Md.). Jan, 2010 | Pubmed ID: 19877180 A Fat Chance for Hepatocyte Transplantation? Gut. Apr, 2009 | Pubmed ID: 19299381 Side Population Cells in Developing Human Liver Are Primarily Haematopoietic Progenitor Cells Experimental Cell Research. Aug, 2009 | Pubmed ID: 19233167 The Isolation and in Vitro Expansion of Hepatic Sca-1 Progenitor Cells Biochemical and Biophysical Research Communications. Apr, 2009 | Pubmed ID: 19233130 Highly Efficient Differentiation of HESCs to Functional Hepatic Endoderm Requires ActivinA and Wnt3a Signaling Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18719101 The Inhibitory Role of Stromal Cell Mesenchyme on Human Embryonic Stem Cell Hepatocyte Differentiation is Overcome by Wnt3a Treatment Cloning and Stem Cells. Sep, 2008 | Pubmed ID: 18479212 Regulation of Alternative Macrophage Activation by Galectin-3 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2008 | Pubmed ID: 18250477 Stem Cell Therapy for Chronic Liver Disease--choosing the Right Tools for the Job Gut. Feb, 2008 | Pubmed ID: 18192451 Progenitor Cell Characterization and Location in the Developing Human Liver Stem Cells and Development. Oct, 2007 | Pubmed ID: 17999598 Selective Depletion of Macrophages Reveals Distinct, Opposing Roles During Liver Injury and Repair The Journal of Clinical Investigation. Jan, 2005 | Pubmed ID: 15630444 Controlling Electrospun Polymer Morphology for Tissue Engineering Demonstrated Using hepG2 Cell Line Thomas S. R. Bate1, Stuart J. Forbes2, Anthony Callanan1 1Institute for Bioengineering, School of Engineering, University of Edinburgh, 2Scottish Centre for Regenerative Medicine, University of Edinburgh JoVE 61043 생체공학
Controlling Electrospun Polymer Morphology for Tissue Engineering Demonstrated Using hepG2 Cell Line Thomas S. R. Bate1, Stuart J. Forbes2, Anthony Callanan1 1Institute for Bioengineering, School of Engineering, University of Edinburgh, 2Scottish Centre for Regenerative Medicine, University of Edinburgh JoVE 61043 생체공학