Wen-Zhi Zhan Department of Physiology and Biomedical Engineering Mayo Clinic Biography Publications Institution JoVE Articles Wen-Zhi Zhan has not added a biography. If you are Wen-Zhi Zhan and would like to personalize this page please email our Author Liaison for assistance. Publications Postnatal Survival of Phrenic Motor Neurons is Promoted by BDNF/TrkB.FL Signaling Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2024 | Pubmed ID: 38511211 Enhanced Diaphragm Muscle Function Upon Satellite Cell Transplantation in Dystrophic Mice International Journal of Molecular Sciences. Feb, 2024 | Pubmed ID: 38473751 Cervical Spinal Cord Hemisection Impacts Sigh and the Respiratory Reset in Male Rats Physiological Reports. Mar, 2024 | Pubmed ID: 38467570 Electrophysiological Effects of BDNF and TrkB Signaling at Type-identified Diaphragm Neuromuscular Junctions Journal of Neurophysiology. Apr, 2023 | Pubmed ID: 36883761 Novel Regenerative Drug, SPG302 Promotes Functional Recovery of Diaphragm Muscle Activity After Cervical Spinal Cord Injury The Journal of Physiology. Jun, 2023 | Pubmed ID: 36815402 Diaphragm Muscle Function in a Mouse Model of Early-onset Spasticity Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2022 | Pubmed ID: 35608200 Cervical Spinal Hemisection Alters Phrenic Motor Neuron Glutamatergic MRNA Receptor Expression Experimental Neurology. Jul, 2022 | Pubmed ID: 35247372 Acute Intrathecal BDNF Enhances Functional Recovery After Cervical Spinal Cord Injury in Rats Journal of Neurophysiology. Jun, 2021 | Pubmed ID: 33949892 Disproportionate Loss of Excitatory Inputs to Smaller Phrenic Motor Neurons Following Cervical Spinal Hemisection The Journal of Physiology. Oct, 2020 | Pubmed ID: 32735344 Diaphragm Muscle Sarcopenia into Very Old Age in Mice Physiological Reports. Jan, 2020 | Pubmed ID: 31908152 Phrenic Motoneuron Structural Plasticity Across Models of Diaphragm Muscle Paralysis The Journal of Comparative Neurology. Dec, 2018 | Pubmed ID: 30411341 Phrenic Motor Neuron Loss in Aged Rats Journal of Neurophysiology. May, 2018 | Pubmed ID: 29412773 Diaphragm Muscle Activity Across Respiratory Motor Behaviors in Awake and Lightly Anesthetized Rats Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2018 | Pubmed ID: 29357493 Impact of Glutamatergic and Serotonergic Neurotransmission on Diaphragm Muscle Activity After Cervical Spinal Hemisection Journal of Neurophysiology. Sep, 2017 | Pubmed ID: 28659464 Chronic TrkB Agonist Treatment in Old Age Does Not Mitigate Diaphragm Neuromuscular Dysfunction Physiological Reports. Jan, 2017 | Pubmed ID: 28082429 BDNF Effects on Functional Recovery Across Motor Behaviors After Cervical Spinal Cord Injury Journal of Neurophysiology. Feb, 2017 | Pubmed ID: 27832605 Motoneuron Glutamatergic Receptor Expression Following Recovery from Cervical Spinal Hemisection The Journal of Comparative Neurology. Apr, 2017 | Pubmed ID: 27650492 TrkB Gene Therapy by Adeno-associated Virus Enhances Recovery After Cervical Spinal Cord Injury Experimental Neurology. Feb, 2016 | Pubmed ID: 26607912 Localized Delivery of Brain-derived Neurotrophic Factor-expressing Mesenchymal Stem Cells Enhances Functional Recovery Following Cervical Spinal Cord Injury Journal of Neurotrauma. Feb, 2015 | Pubmed ID: 25093762 TrkB Kinase Activity is Critical for Recovery of Respiratory Function After Cervical Spinal Cord Hemisection Experimental Neurology. Nov, 2014 | Pubmed ID: 24910201 Targeted Delivery of TrkB Receptor to Phrenic Motoneurons Enhances Functional Recovery of Rhythmic Phrenic Activity After Cervical Spinal Hemisection PloS One. 2013 | Pubmed ID: 23724091 Motoneuron BDNF/TrkB Signaling Enhances Functional Recovery After Cervical Spinal Cord Injury Experimental Neurology. Sep, 2013 | Pubmed ID: 23583688 Prolonged C2 Spinal Hemisection-induced Inactivity Reduces Diaphragm Muscle Specific Force with Modest, Selective Atrophy of Type IIx And/or IIb Fibers Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2013 | Pubmed ID: 23195635 Non-stationarity and Power Spectral Shifts in EMG Activity Reflect Motor Unit Recruitment in Rat Diaphragm Muscle Respiratory Physiology & Neurobiology. Jan, 2013 | Pubmed ID: 22986086 Reduced Ribosomal Protein S6 Phosphorylation After Progressive Resistance Exercise in Growing Adolescent Rats Journal of Strength and Conditioning Research. Jun, 2012 | Pubmed ID: 22614147 Phrenic Motoneuron Expression of Serotonergic and Glutamatergic Receptors Following Upper Cervical Spinal Cord Injury Experimental Neurology. Mar, 2012 | Pubmed ID: 22227062 Structure-activity Relationships in Rodent Diaphragm Muscle Fibers Vs. Neuromuscular Junctions Respiratory Physiology & Neurobiology. Jan, 2012 | Pubmed ID: 22063925 Inhaled Carbon Monoxide Attenuates Myocardial Inflammatory Cytokine Expression in a Rat Model of Cardiopulmonary Bypass The Journal of Extra-corporeal Technology. Sep, 2011 | Pubmed ID: 22164452 Chronic Assessment of Diaphragm Muscle EMG Activity Across Motor Behaviors Respiratory Physiology & Neurobiology. Jul, 2011 | Pubmed ID: 21414423 Intracellular Signaling Pathways Regulating Net Protein Balance Following Diaphragm Muscle Denervation American Journal of Physiology. Cell Physiology. Feb, 2011 | Pubmed ID: 21084642 Neuregulin-1 at Synapses on Phrenic Motoneurons The Journal of Comparative Neurology. Oct, 2010 | Pubmed ID: 20878784 Diaphragm Motor Unit Recruitment in Rats Respiratory Physiology & Neurobiology. Aug, 2010 | Pubmed ID: 20620243 Impairment of Diaphragm Muscle Force and Neuromuscular Transmission After Normothermic Cardiopulmonary Bypass: Effect of Low-dose Inhaled CO American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2010 | Pubmed ID: 20089713 Effect of Collagen Digestion on the Passive Elastic Properties of Diaphragm Muscle in Rat Medical Engineering & Physics. Jan, 2010 | Pubmed ID: 19945332 Correlation of Respiratory Activity of Contralateral Diaphragm Muscles for Evaluation of Recovery Following Hemiparesis Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2009 | Pubmed ID: 19965125 Retrograde Labeling of Phrenic Motoneurons by Intrapleural Injection Journal of Neuroscience Methods. Sep, 2009 | Pubmed ID: 19559048 The Effect of Denervation on Protein Synthesis and Degradation in Adult Rat Diaphragm Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2009 | Pubmed ID: 19520837 Developmental Effects on Myonuclear Domain Size of Rat Diaphragm Fibers Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2008 | Pubmed ID: 18187618 Effect of Denervation on ATP Consumption Rate of Diaphragm Muscle Fibers Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2007 | Pubmed ID: 17556500 Endovascular Treatment of Experimental Aneurysms by Use of Fibroblast-coated Platinum Coils: an Angiographic and Histopathologic Study Stroke. Jan, 2007 | Pubmed ID: 17122421 EMG-based Detection of Inspiration in the Rat Diaphragm Muscle Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2006 | Pubmed ID: 17946030 Mechanisms Underlying Myosin Heavy Chain Expression During Development of the Rat Diaphragm Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2006 | Pubmed ID: 16873604 Neuregulin-dependent Protein Synthesis in C2C12 Myotubes and Rat Diaphragm Muscle American Journal of Physiology. Cell Physiology. Nov, 2006 | Pubmed ID: 16790500 Denervation Effects on Myonuclear Domain Size of Rat Diaphragm Fibers Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2006 | Pubmed ID: 16410375 Diaphragm Dysfunction in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. Jul, 2005 | Pubmed ID: 15849324 Synaptic Vesicle Cycling at Type-identified Diaphragm Neuromuscular Junctions Muscle & Nerve. Dec, 2004 | Pubmed ID: 15478121 Neurotrophins Improve Neuromuscular Transmission in the Adult Rat Diaphragm Muscle & Nerve. Mar, 2004 | Pubmed ID: 14981737 Regulation of Neuromuscular Transmission by Neurotrophins Sheng Li Xue Bao : [Acta Physiologica Sinica]. Dec, 2003 | Pubmed ID: 14695476 Myocardial Contractility by Strain Echocardiography: Comparison with Physiological Measurements in an in Vitro Model American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2003 | Pubmed ID: 12907429 Denervation-induced Changes in Myosin Heavy Chain Expression in the Rat Diaphragm Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2003 | Pubmed ID: 12704093 Effects of Hypothyroidism on Maximum Specific Force in Rat Diaphragm Muscle Fibers Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2002 | Pubmed ID: 11896017 Cervical Dorsal Rhizotomy Enhances Serotonergic Innervation of Phrenic Motoneurons and Serotonin-dependent Long-term Facilitation of Respiratory Motor Output in Rats The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 1998 | Pubmed ID: 9763486 Assessing Functional Recovery of Eupneic Diaphragm Activity Following Unilateral Cervical Spinal Cord Injury in Rats Obaid U. Khurram1, Matthew J. Fogarty1, Wen-Zhi Zhan1, Carlos B. Mantilla1,2, Gary C. Sieck1,2 1Department of Physiology and Biomedical Engineering, Mayo Clinic, 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic JoVE 66828 신경과학
Assessing Functional Recovery of Eupneic Diaphragm Activity Following Unilateral Cervical Spinal Cord Injury in Rats Obaid U. Khurram1, Matthew J. Fogarty1, Wen-Zhi Zhan1, Carlos B. Mantilla1,2, Gary C. Sieck1,2 1Department of Physiology and Biomedical Engineering, Mayo Clinic, 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic JoVE 66828 신경과학
