Identifying DNA Damage in Prophase-Arrested Oocytes of Mice

June 23, 2023

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Chrysoula Zorzompokou², Marios Ipeirotis², Marios Kaisar Martzoukos, Petros Marangos²

¹Department of Biological Applications and Technology,University of Ioannina, ²Biomedical Research Institute,Foundation for Research and Technology

Summary

Maintaining oocyte genome integrity is necessary to ensure the genetic fidelity in the resulting embryo. Here, we present an accurate protocol for detecting DNA double-strand breaks in mammalian female germ cells.

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