Examining Tumor Cell Dissemination from Lung Metastases

July 07, 2023

Sporing av spredning av tumorceller fra lungemetastaser ved hjelp av fotokonvertering

Surgical Protocol for the Selective Photoconversion of Lung Metastases

Madeline Friedman-DeLuca², Prachiben P. Patel², Burcu Karadal-Ferrena², Nicole D. Barth², Camille L. Duran², Xianjun Ye^2,3, Michael Papanicolaou⁴, John S. Condeelis^3,4,5,6,7, Maja H. Oktay^2,3,5,6,7, Lucia Borriello*^1,2,8, David Entenberg*^1,2,3,5,6

¹Department of Pathology,Albert Einstein College of Medicine/Montefiore Medical Center, ²Cancer Dormancy and Tumor Microenvironment Institute,Albert Einstein College of Medicine/Montefiore Medical Center, ³Gruss-Lipper Biophotonics Center,Albert Einstein College of Medicine/Montefiore Medical Center, ⁴Department of Cell Biology,Albert Einstein College of Medicine/Montefiore Medical Center, ⁵Montefiore Einstein Cancer Center,Albert Einstein College of Medicine/Montefiore Medical Center, ⁶Integrated Imaging Program for Cancer Research,Albert Einstein College of Medicine/Montefiore Medical Center, ⁷Department of Surgery,Albert Einstein College of Medicine/Montefiore Medical Center, ⁸Department of Cancer and Cellular Biology, Lewis Katz School of Medicine,Fox Chase Cancer Center

Summary

Vi presenterer en metode for å studere tumorcelleformidling fra lungemetastaser med kirurgisk protokoll for selektiv fotokonvertering av lungemetastaser, etterfulgt av identifisering av formidlede tumorceller i tertiære organer.

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