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Cyclic Mechanical Loading for Inducing Tendinopathy in Rat Achilles Tendon

March 01, 2024
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Summary

This protocol presents a testing system used to induce quantifiable and controlled fatigue injuries in a rat Achilles tendon for an in-vivo model of overuse-induced tendinopathy. The procedure consists of securing the rat’s ankle to a joint actuator that performs passive ankle dorsiflexion with a custom-written MATLAB script.