National Clinical Research Center for Otolaryngologic Diseases 1 article published in JoVE Medicine The Miniature Pig: A Large Animal Model for Cochlear Implant Research Xiaojun Ji*1,2,3,4, Yi Luo*1,2,3,4, Weiwei Guo1,2,3,4, Fei Ji1,2,3,4, Shuolong Yuan1,2,3,4, Liangwei Xu1,2,3,4, Wei Chen*1,2,3,4 1College of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, 2National Clinical Research Center for Otolaryngologic Diseases, 3Key Lab of Hearing Science, Ministry of Education, 4Beijing Key Lab of Hearing Impairment for Prevention and Treatment Miniature pigs (mini-pigs) are an ideal large animal model for research into cochlear implants. Cochlear implantation surgery in mini-pigs can be utilized to provide initial evidence of the safety and potential performance of novel electrode arrays and surgical approaches in a living system similar to human beings.