Birla Institute of Technology and Science 1 article published in JoVE Medicine Retinal Pathophysiological Evaluation in a Rat Model Manisha Malani1, Jayabalan Nirmal1 1Translational Pharmaceutics Research Laboratory (TPRL), Department of Pharmacy, Birla Institute of Technology & Science — Pilani, Hyderabad Campus Diabetic retinopathy is one of the leading causes of blindness. Histology, blood-retinal barrier breakdown assay, and fluorescence angiography are valuable techniques to understand the pathophysiology of the retina, which could further enhance the efficient drug screening against diabetic retinopathy.