University Medical Center Gottigen (UMG) 1 article published in JoVE Developmental Biology Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration Christine M. Rostosky1,2, Ira Milosevic1,2 1European Neuroscience Institute (ENI), 2University Medical Center Göttigen (UMG) In this study, we demonstrate the use of kinematic gait analysis based on ventral plane imaging to monitor the subtle changes in motor coordination as well as the progression of neurodegeneration with advancing age in mouse models (e.g., endophilin mutant mouse lines).