Centre Hospitalier Universitaire de Nice 1 article published in JoVE Medicine Echocardiographic and Histological Examination of Cardiac Morphology in the Mouse Delphine Baudouy1, Jean-François Michiels1,2, Ana Vukolic3, Kay-Dietrich Wagner1, Nicole Wagner1 1Université Côte d’Azur, CNRS, INSERM, iBV, 2Department of Pathology, CHU Nice, 3Institute for Molecular Health Sciences, ETH Zurich Echocardiographic examination is frequently used in mice. Expensive high-resolution ultrasound devices have been developed for this purpose. This protocol describes an affordable echocardiographic procedure combined with histological morphometric analyses to determine cardiac morphology.