Bahauddin Zakariya University 1 article published in JoVE Chemistry Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides Alexandros Lamprou1, Hongxia Wang1,4, Adeela Saeed2, Frantisek Svec1, David Britt1, Fernando Maya3 1The Molecular Foundry, E. O. Lawrence Berkeley National Laboratory, 2Institute of Chemical Sciences, Bahauddin Zakariya University, 3Department of Chemistry, University of the Balearic Islands, 4Beijing Key Lab of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology A procedure for the preparation of porous hybrid separation media composed of a macroporous polymer monolith internally coated by a high surface area microporous coordination polymer is presented.