University of Aachen Medical Center View Institution's Website 1 article published in JoVE Medicine Pseudofracture: An Acute Peripheral Tissue Trauma Model Sophie S. Darwiche1, Philipp Kobbe2, Roman Pfeifer2, Lauryn Kohut1, Hans-Christoph Pape2, Timothy Billiar1 1Department of Surgery, University of Pittsburgh, 2Department of Orthopedic Surgery, University of Aachen Medical Center Pseudofracture, a reproducible murine model of sterile musculoskeletal trauma, allows for evaluation of late term post-traumatic immune responses. This article describes the procedural execution of the model step by step, including the potential for experimental model combinations to permit study of multiple trauma.