UConn School of Medicine 1 article published in JoVE Neuroscience A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice Mitch R. Paro*1, Daylin Gamiotea Turro*1, Michael Mcgonnigle1, Ketan R. Bulsara2, Rajkumar Verma1 1Department of Neuroscience, UConn School of Medicine, 2Division of Neurosurgery, UConn School of Medicine The protocol aims to provide methods for encephalomyosynangiosis-grafting of a vascular temporalis muscle flap on the pial surface of ischemic brain tissue-for the treatment of non-moyamoya acute ischemic stroke. The approach's efficacy in increasing angiogenesis is evaluated using a transient middle cerebral artery occlusion model in mice.